3.A.1.204.27
Multidrug resistancd protein, ABCG19 (Wbc19), of 725 aas and 6 TMSs with a domain order C-M. Confers resistance to kanamycin (Mentewab and Stewart 2005).
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| Accession Number: | Q9M3D6 |
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| Protein Name: | ABC transporter G family member 19 |
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| Length: | 725 |
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| Molecular Weight: | 80657.00 |
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| Species: | Arabidopsis thaliana (Mouse-ear cress) [3702] |
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| Number of TMSs: | 6 |
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| Location1 / Topology2 / Orientation3: |
Vacuole membrane1 / Multi-pass membrane protein2 |
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| Substrate |
kanamycin, drug |
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1: MNLSLSGRKI AMTRVSAETQ YITPIGSPTL DELLKDCDSF RKGDSGDGVK SDDPAHHIID
61: VEALYVKPVP YVLNFNNLQY DVTLRRRFGF SRQNGVKTLL DDVSGEASDG DILAVLGASG
121: AGKSTLIDAL AGRVAEGSLR GSVTLNGEKV LQSRLLKVIS AYVMQDDLLF PMLTVKETLM
181: FASEFRLPRS LSKSKKMERV EALIDQLGLR NAANTVIGDE GHRGVSGGER RRVSIGIDII
241: HDPIVLFLDE PTSGLDSTNA FMVVQVLKRI AQSGSIVIMS IHQPSARIVE LLDRLIILSR
301: GKSVFNGSPA SLPGFFSDFG RPIPEKENIS EFALDLVREL EGSNEGTKAL VDFNEKWQQN
361: KISLIQSAPQ TNKLDQDRSL SLKEAINASV SRGKLVSGSS RSNPTSMETV SSYANPSLFE
421: TFILAKRYMK NWIRMPELVG TRIATVMVTG CLLATVYWKL DHTPRGAQER LTLFAFVVPT
481: MFYCCLDNVP VFIQERYIFL RETTHNAYRT SSYVISHSLV SLPQLLAPSL VFSAITFWTV
541: GLSGGLEGFV FYCLLIYASF WSGSSVVTFI SGVVPNIMLC YMVSITYLAY CLLLSGFYVN
601: RDRIPFYWTW FHYISILKYP YEAVLINEFD DPSRCFVRGV QVFDSTLLGG VSDSGKVKLL
661: ETLSKSLRTK ITESTCLRTG SDLLAQQGIT QLSKWDCLWI TFASGLFFRI LFYFALLFGS
721: RNKRT