3.A.1.204.45 ABC transporter G family member 11; ABCG.11; CUTICULAR DEFECT AND ORGAN FUSION 1 protein; Protein DESPERADO; PERMEABLE LEAVES 1; White-brown complex homolog protein 11, AtWBC11, of 703 aas with 6 TMSs (C-terminal) in a 5 + 1 TMS arrangement. It is involved in cuticle development and prevention of organ fusion (Luo et al. 2007). AbcG transporters are required for export of diverse cuticular lipids (McFarlane et al. 2010). It is required for cuticle, root suberin and pollen coat development by controlling cutin and maybe wax transport to the extracellular matrix (Le Hir et al. 2013). It is also involved in developmental plasticity and stress responses. Together with ABCG9 and ABCG14, it is required for vascular development by regulating lipid/sterol homeostasis (Le Hir et al. 2013). May be a transporter of lignin precursors during tracheary element differentiation (Takeuchi et al. 2018). It is expressed in seedlings, roots, stems, leaves, flowers, and siliques, mostly in epidermis, trichomes, vasculatures and developing tissues (Le Hir et al. 2013).
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Accession Number: | Q8RXN0 |
Protein Name: | ABC transporter G family member 11 |
Length: | 703 |
Molecular Weight: | 78413.00 |
Species: | Arabidopsis thaliana (Mouse-ear cress) [3702] |
Number of TMSs: | 7 |
Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
Substrate |
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1: MEIEASRQQT TVPVSVGGGN FPVGGLSPLS EAIWREKAPT EFVGDVSARL TWQDLTVMVT
61: MGDGETQNVL EGLTGYAEPG SLTALMGPSG SGKSTMLDAL ASRLAANAFL SGTVLLNGRK
121: TKLSFGTAAY VTQDDNLIGT LTVRETIWYS ARVRLPDKML RSEKRALVER TIIEMGLQDC
181: ADTVIGNWHL RGISGGEKRR VSIALEILMR PRLLFLDEPT SGLDSASAFF VTQTLRALSR
241: DGRTVIASIH QPSSEVFELF DRLYLLSGGK TVYFGQASDA YEFFAQAGFP CPALRNPSDH
301: FLRCINSDFD KVRATLKGSM KLRFEASDDP LEKITTAEAI RLLVDYYHTS DYYYTAKAKV
361: EEISQFKGTI LDSGGSQASF LLQTYTLTKR SFINMSRDFG YYWLRLLIYI LVTVCIGTIY
421: LNVGTSYSAI LARGSCASFV FGFVTFMSIG GFPSFVEDMK VFQRERLNGH YGVAAFVIAN
481: TLSATPFLIM ITFISGTICY FMVGLHPGFT HYLFFVLCLY ASVTVVESLM MAIASIVPNF
541: LMGIIIGAGI QGIFMLVSGF FRLPNDIPKP FWRYPMSYIS FHFWALQGQY QNDLRGLTFD
601: SQGSAFKIPG EYVLENVFQI DLHRSKWINL SVILSMIIIY RIIFFIMIKT NEDVTPWVRG
661: YIARRRMKQK NGTQNTTVAP DGLTQSPSLR NYIATRTDGA RRW