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| Accession Number: | P41820 |
| Protein Name: | Brefeldin A resistance protein aka Bfr1 |
| Length: | 1530 |
| Molecular Weight: | 171751.00 |
| Species: | Schizosaccharomyces pombe (Fission yeast) [4896] |
| Number of TMSs: | 13 |
| Location1 / Topology2 / Orientation3: | Membrane1 / Multi-pass membrane protein2 |
| Substrate | actinomycin D, cerulenin, brefeldin A |
Cross database links:
| RefSeq: | NP_587932.3 |
|---|---|
| Entrez Gene ID: | 2539195 |
| Pfam: | PF01061 PF00005 PF06422 |
| KEGG: | spo:SPCC18B5.01 |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0005886
C:plasma membrane
GO:0005524
F:ATP binding
GO:0042626
F:ATPase activity, coupled to transmembrane m...
GO:0033554
P:cellular response to stress
GO:0046677
P:response to antibiotic
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References (4)[1] “bfr1+, a novel gene of Schizosaccharomyces pombe which confers brefeldin A resistance, is structurally related to the ATP-binding cassette superfamily.” Nagao K.et.al. 7883711 [2] “Characterization of a novel Schizosaccharomyces pombe multidrug resistance transporter conferring brefeldin A resistance.” Turi T.G.et.al. 7646493 | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MNQNSDTTHG QALGSTLNHT TEVTRISNSS DHFEDSSSNV DESLDSSNPS SNEKASHTNE 61: EYRSKGNQSY VPSSSNEPSP ESSSNSDSSS SDDSSVDRLA GDPFELGENF NLKHYLRAYK 121: DSLQRDDIIT RSSGVCMRDH SVYGVGSGYE FLKTFPDIFL QPYRAITEKQ VVEKAILSHC 181: HALANAGELV MVLGQPGSGC STFLRSVTSD TVHYKRVEGT THYDGIDKAD MKKFFPGDLL 241: YSGENDVHFP SLTTAETLDF AAKCRTPNNR PCNLTRQEYV SRERHLIATA FGLTHTFNTK 301: VGNDFVRGVS GGERKRVTIS EGFATRPTIA CWDNSTRGLD SSTAFEFVNV LRTCANELKM 361: TSFVTAYQAS EKIYKLFDRI CVLYAGRQIY YGPADKAKQY FLDMGFDCHP RETTPDFLTA 421: ISDPKARFPR KGFENRVPRT PDEFEQMWRN SSVYADLMAE MESYDKRWTE TTPASSEAPE 481: KDNFGSDISA TTKHELYRQS AVAEKSKRVK DTSPYTVTFS QQLWYCLARS WERYINDPAY 541: IGSMAFAFLF QSLIIGSIFY DMKLNTVDVF SRGGVLFFSI LFCALQSLSE IANMFSQRPI 601: IAKHRASALY HPAADVISSL IVDLPFRFIN ISVFSIVLYF LTNLKRTAGG FWTYFLFLFI 661: GATCMSAFFR SLAGIMPNVE SASALGGIGV LAIAIYTGYA IPNIDVGWWF RWIAYLDPLQ 721: FGFESLMINE FKARQFECSQ LIPYGSGYDN YPVANKICPV TSAEPGTDYV DGSTYLYISF 781: NYKTRQLWRN LAIIIGYYAF LVFVNIVASE TLNFNDLKGE YLVFRRGHAP DAVKAAVNEG 841: GKPLDLETGQ DTQGGDVVKE SPDNEEELNK EYEGIEKGHD IFSWRNLNYD IQIKGEHRRL 901: LNGVQGFVVP GKLTALMGES GAGKTTLLNV LAQRVDTGVV TGDMLVNGRG LDSTFQRRTG 961: YVQQQDVHIG ESTVREALRF SAALRQPASV PLSEKYEYVE SVIKLLEMES YAEAIIGTPG 1021: SGLNVEQRKR ATIGVELAAK PALLLFLDEP TSGLDSQSAW SIVCFLRKLA DAGQAILCTI 1081: HQPSAVLFDQ FDRLLLLQKG GKTVYFGDIG EHSKTLLNYF ESHGAVHCPD DGNPAEYILD 1141: VIGAGATATT NRDWHEVWNN SEERKAISAE LDKINASFSN SEDKKTLSKE DRSTYAMPLW 1201: FQVKMVMTRN FQSYWREPSI LMSKLALDIF AGLFIGFTFY NQGLGVQNIQ NKLFAVFMAT 1261: VLAVPLINGL QPKFIELRNV FEVREKPSNI YSWVAFVFSA IIVEIPFNLV FGTLFFLCWF 1321: YPIKFYKHIH HPGDKTGYAW LLYMFFQMYF STFGQAVASA CPNAQTASVV NSLLFTFVIT 1381: FNGVLQPNSN LVGFWHWMHS LTPFTYLIEG LLSDLVHGLP VECKSHEMLT INPPSGQTCG 1441: EYMSAFLTNN TAAGNLLNPN ATTSCSYCPY QTADQFLERF SMRYTHRWRN LGIFVGYVFF 1501: NIFAVLLLFY VFRVMKLRST WLGKKITGTG