3.A.1.205.28
ABCG30 or PDR2 of 1400 aas and 12 TMSs in a C-M-C-M domain arrangement. Responds to abiotic stresses such as heavy metals (Cd2+, Pb2+, etc), and is regulated by hormones related to pathogenic defenses (Crouzet et al. 2006) . It may be a heavy metal efflux pump, but may also transport abscisic acid, influencing developmental processes, including seed and bud dormancy, the control of organ size and stomatal closure (Lefèvre and Boutry 2018). This system may be a biomarkers responding to abiotic (heavey metal ion) stress (Zhang et al. 2022).
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| Accession Number: | Q8GZ52 |
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| Protein Name: | ABC transporter G family member 30 |
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| Length: | 1400 |
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| Molecular Weight: | 157768.00 |
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| Species: | Arabidopsis thaliana (Mouse-ear cress) [3702] |
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| Number of TMSs: | 11 |
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| Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
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| Substrate |
cadmium(2+), lead(2+), 2-cis-abscisic acid |
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1: MIQTGEEDEE KATSLEVEFA SGNGVDDEEE LRLQWATVER LPTFKRVTTA LLARDEVSGK
61: GRVIDVTRLE GAERRLLIEM LVKQIEDDNL RLLRKIRKRI DKVGIELPTV EVRFNNLSVE
121: AECQVIHGKP IPTLWNTIKG LLSEFICSKK ETKIGILKGV SGIVRPGRMT LLLGPPGCGK
181: TTLLQALSGK FSDSVKVGGE VCYNGCSLSE FIPEKTSSYI SQNDLHIPEL SVRETLDFSA
241: CCQGIGSRME IMKEISRMEK LQEIIPDPAV DAYMKATSVE GLKNNLQTDY ILKILGLDIC
301: ADTRVGDATR PGISGGEKRR LTTGELVVGP ATTLFMDEIS NGLDSSTTFQ IVSCLQQLAH
361: IAEATILISL LQPAPETFEL FDDVILMGEG KIIYHAPRAD ICRFFEEFGF KCPERKGVAD
421: FLQEIMSKKD QEQYWCHRDK PYSYISVDSF INKFKESNLG LLLKEELSKP FNKSQTRKDG
481: LCYKKYSLGK WEMLKACSRR EFLLMKRNSF IYLFKSALLV FNALVTMTVF LQVGATTDSL
541: HGNYLMGSLF TALFRLLADG LPELTLTISR LGVFCKQKDL YFYPAWAYAI PSIILKIPLS
601: VLDSFIWTLL TYYVIGYSPE VKRFFLQFLI LSTFNLSCVS MFRAIAAIFR TIIASTITGA
661: ISILVLSLFG GFVIPKSSMP AWLGWGFWLS PLSYAEIGLT ANEFFSPRWS KVISSKTTAG
721: EQMLDIRGLN FGRHSYWTAF GALVGFVLFF NALYVLALTY QNNPQRSRAI ISHEKYSRPI
781: EEDFKPCPKI TSRAKTGKII LPFKPLTVTF QNVQYYIETP QGKTRQLLSD ITGALKPGVL
841: TSLMGVSGAG KTTLLDVLSG RKTRGIIKGE IKVGGYPKVQ ETFARVSGYC EQFDIHSPNI
901: TVEESLKYSA WLRLPYNIDS KTKNELVKEV LETVELDDIK DSVVGLPGIS GLSIEQRKRL
961: TIAVELVANP SIIFMDEPTT GLDARAAAIV MRAVKNVAET GRTVVCTIHQ PSIDIFETFD
1021: ELILMKNGGQ LVYYGPPGQN SSKVIEYFES FSGLPKIQKN CNPATWILDI TSKSAEEKLG
1081: IDFSQSYKDS TLYKQNKMVV EQLSSASLGS EALRFPSQFS QTAWVQLKAC LWKQHYSYWR
1141: NPSHNITRIV FILLDSTLCG LLFWQKAEDI NNQQDLISIF GSMYTLVVFP GMNNCAAVIN
1201: FIAAERNVFY RERFARMYSS WAYSFSQVLI EVPYSLLQSL LCTIIVYPTI GYHMSVYKMF
1261: WSLYSIFCSL LIFNYSGMLM VALTPNIHMA VTLRSSFFSM LNLFAGFVIP KQKIPKWWIW
1321: MYYLSPTSWV LEGLLSSQYG DVDKEILVFG EKKRVSAFLE DYFGYKHESL AVVAFVLIAY
1381: PIIVATLFAF FMSKLSFQKK