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3.A.1.205.33
ABC transporter C family member 4, ABCC4, of 1495 aas and 17 TMSs in a 5 + 6 (2 + 2 + 2) + 6 (2 + 2 + 2 TMS arrangement (M + M + C + M + C overall domain order).  In Crocus sativus, it transports, in saffrom stigmas, crocins, a mixture of apocarotenoid glycosides (Demurtas et al. 2020). Apocarotenoids are carotenoid derivatives produced by the nonenzymatic or enzymatic cleavage of carotenoids, followed by different enzymatic modifications. In plants, apocarotenoids play various roles, such as attraction of pollinators and seeds dispersal, defense against pathogens and herbivores, protection against photo-oxidative stresses, stimulation and inhibition of plant growth and regulation of biological processes in the case of phytohormones abscisic acid and strigolactones. While carotenoids are in general plastid-localized metabolites, apocarotenoids can reach different final destinations inside or outside the cell (Demurtas et al. 2020).

ABCC4

Accession Number:PKU85821.1
Protein Name:PKU85821.1 ABC transporter C family member 4 [Dendrobium catenatum]
Length:1496
Molecular Weight:
Species:Dendrobium catenatum [906689]
Number of TMSs:20
Substrate

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSFSISAFTC SPPPGATVGK LLYFVFLSPC PQRALFSLLD LLFLLTLLLF VIQKLLSRRH 
61:	ESNSDAAKPL LPTSSAVRTT WRFNLPLAIS SILAAAFLVL LVLALALDKS SPFSWRLLQS 
121:	IFFSFQFLSH LAAAAVIAHE KRFRAISHPL TLRLFWIFSF LLSILLTVSA VLRLFSSSAN 
181:	FPDGIASLVF LLFSAALLVF ALSPSTGFHS QLSSSSPSST GDSNLSEDSE SKPNVTAYTT 
241:	ASLLSRLTWS WMNPLLAKGY KSPLKLQDVP SLAPEHQAQR LYNLFNSHWP RPAIKSHHPV 
301:	RTTLLRCFWP QLLLTASLAV LRLCVMYVGP TLINRFIDFA SGRRSSIYEG YYLCLTLLAA 
361:	KFVEVLCSHH YNFHSQKTGM LIRSTLITTL YRKGLRLSCS ARQSHGLGMI VNYMAVDAQQ 
421:	LSDMMLQIHY IWLMPLQVGV ALALLYVYLG PSVTSAVVGI IAVMVFVVFG TRRNNLFQFS 
481:	LMGMRDKRMK ATNEMLNYMR VIKFQAWEEH FNKRIQGFRS EEFGWLSRFM YSISGNIIVL 
541:	WSAPLVISSL VFGTCIAAGV RLDAGIVFTA TSFFKILQEP MRNFPQALIS ASQAMISLER 
601:	LDAYMTSGEL DEGAVEQVLS GYAVDAPAVE VCEGTFGWED DVSADTAWLK RVNVRIPRGA 
661:	VAAVVGTVGS GKSSFLSCLV GEMHRISGKV RVCGSMAYVA QTAWIQNGTI QDNILFGLPL 
721:	NQQKYKEVIR VCCLTKDLEM MEFGDQTEIG ERGINLSGGQ KQRIQLARAV YQDSDVYLLD 
781:	DVFSAVDAHT GSEIFKECIR GALKDKTVIL VTHQVDFLHN ADLILVMRDG MIVQSGKYNE 
841:	ILNAGADFAA LVAAHDSSME LVEHGPPEQV RMDSPSKQGD QTITNDEKSK DESSVISPKT 
901:	EKSSAKLIKD EERETGKVSL NVYKTYITEA WGWWGVIAVL IVSLLWQGSL MASDYWLALS 
961:	TSANNASSFN PSQFIEVYVI IAVISVILVA GRSFLVTYWG LKTAQIFFKQ ILNSILHAPM 
1021:	SFFDTTPSGR ILSRASSDQT NVDLFLPFFV GLTVSMYITV LSILIVTIQV AWPTLFFIIP 
1081:	LAWLNVWYRG YYLTTSRELT RLDSITKAPV IHHFSETIQG VMTIRCFKKE ERFSQENINR 
1141:	VNASLTMDFH NNGSNEWMGF RLELIGTVIL CISALSMVML PSNFIKPEYV GLSLSYGLSL 
1201:	NSVLFWAIWI SCFLENRMVS VERLKQFSSI PPEAPWRIKD RLPSPNWPTH GDIILRDLKV 
1261:	RYRPNTPLVL HGITLDIHGG EKIGVVGRTG SGKSTLIQAL FRIVEPSGGK IIIDGIDICI 
1321:	LGLHDLRSRF GIIPQEPVLF EGTVRSNVDP VGQYTDDEIW QSLERCQLKQ AVAAKPEKLD 
1381:	ALVVDNGENW SVGQRQLFCL GRVLLKKSRI LFMDEATASV DSQTDGFIQK IIREDFSNCT 
1441:	IISIAHRIPT VMDCDRVLVV DSGLAKEFDS PTNLIERPSL FGALVQEYAN RSSDL