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| Accession Number: | P78577 |
| Protein Name: | AtrB |
| Length: | 1426 |
| Molecular Weight: | 158928.00 |
| Species: | Aspergillus nidulans [162425] |
| Number of TMSs: | 11 |
| Location1 / Topology2 / Orientation3: | Cell membrane1 / Lipid-anchor2 |
| Substrate | rhodamine 6G, dicarboximide, camptothecin, 1H-benzimidazole, 3,6-diamino-10-methylacridinium chloride, 1H-pyrrole, pentachloronitrobenzene, anilinopyrimidine fungicide, fungicide |
Cross database links:
| Pfam: | PF01061 PF00005 PF06422 |
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Gene Ontology
GO:0016021
C:integral to membrane
GO:0005524
F:ATP binding
GO:0042626
F:ATPase activity, coupled to transmembrane m...
GO:0006810
P:transport
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References (2)[1] “Multidrug resistance in Aspergillus nidulans involves novel ATP-binding cassette transporters.” Del Sorbo G.et.al. 9180695 [2] “The ABC transporter AtrB from Aspergillus nidulans mediates resistance to all major classes of fungicides and some natural toxic compounds.” Andrade A.C.et.al. 10931903
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External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MSTLTVGDTA LPRESRETMV SIQGIRIVNY SSRRGFRFHN KIQMSAVPMA GLLMPQVKEQ 61: NEREAESGFK RRELGVTWQN LSVEVVSADA AVQENFLSQF NVPKLARESR NKPPLRTILD 121: NSHGCVKPGE MLLVLGRPGS GCTTLLKMLA NQRLGYKAVQ GDVRYGSMTA KEAEQYRGQI 181: VMNTQEELFF PSLTVGETMD FATRLKVPNR LPNGVESPEA YREEYKKFLL QSMGISHTVD 241: TKVGNEFIRG VSGGERKRVS IIECLGTRAS VFCWDNSTRG LDASTALEWT KTIRTMTDVL 301: GLSTIVTLYQ AGNGIYDLFD KVLVLDEAKQ IYYGPMTQAR PYMETLDFVC REGSNVADFL 361: TGVTVPTERK IRSGFEARFP RNADAMLEEY NKSAVKADMI SEYDYPDSEY AKLRTEDFKQ 421: AIAEEKAKQL PKSSPFTVDF MNQVKICVTR QYQILWGDKA TFIIKQVSTL IQALIAGSLF 481: YDAPNNSGGL FVKSGALFFS LLYNSLLAMA EVTESFQGRP VLIKHKSFAF FHPAAFCIAQ 541: IAADIPVLIF QVTIFALPVY FMVGLEMDAG VFFTYWILVF ATTMAMTAVF RACGAAFKTF 601: DDASKVSGFL ISALIMYTGY MIRKPEMHPW FVWIYWIDPL AYGFDALLSN EFHGKIIPCV 661: GTNLVPAGPG YENATTQSCT GVGGSIPGRN YVTGDDYLAS LSYSHGHVWR NFGILWAWWA 721: LFVVVTIIAT SRWKGASENG PSLLIPRESV EKHRQHGHRD EESQSNEKTS TKGKSEGVQD 781: SSDIDNQLVR NTSVFTWKDL CYTVKTPSGD RQLLDHVYGW VKPGMLGALM GSSGAGKTTL 841: LDVLAQRKTA GTIQGSVLVD GRPLPVSFQR SAGYCEQFDV HEPYATVREA LEFSALLRQP 901: RTTPREEKLK YVDVIIDLLE LHDIADTLIG RVGAGLSVEQ RKRVTIGVEL VSKPSILIFL 961: DEPTSGLDGQ SAYNTVRFLR KLADVGQAVL VTIHQPSAQL FGEFDSLLLL AKGGKMVYFG 1021: DIGDNGSTVK EYFGRHGAPC PPNANPGEHM IDVVSGSLSQ GRDWHEVWKA SPEHTNAQKE 1081: LDRIISEAGS KPPGTVDDGH EFAMPLWQQT VIVTKRTCLG VYRNTDYVNN KLALHIGSAL 1141: FNGFSFWKMG ASVGELQFKL FVLFNFIFAA PGGIGQVQAL FIERRDIYDA REKKSRIFSW 1201: VGFVTGLIVS ELPYLVLCAV LYFVCFYYQT GLPTSSDKAG AVFFVMLLYE GLYTGIGQFI 1261: SAYAPNAVFA TLTNPLVIGT LVSFCGVLVP YGQIQEFWRY WIYWLNPFNY LMGSLLTFTI 1321: FDVDIKCRES EFATFDPPNG SSCIDYLSTI FKGWGVSANL INPDATSQCQ VCQYTRGSDY 1381: LYSLNLKDYY YGWRDTAIVA LFVLSSYALV YGLMKLRTKA SKKAEE