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| Accession Number: | Q9LK64 |
| Protein Name: | Multidrug resistance-associated protein 3 aka EST2 aka MRP3 |
| Length: | 1514 |
| Molecular Weight: | 168971.00 |
| Species: | Arabidopsis thaliana (Mouse-ear cress) [3702] |
| Number of TMSs: | 17 |
| Location1 / Topology2 / Orientation3: | Membrane1 / Multi-pass membrane protein2 |
| Substrate | cadmium(2+), red chlorophyll catabolite(2-), anthocyanin cation, glutathione conjugate |
Cross database links:
| RefSeq: | NP_187915.1 NP_850575.1 |
|---|---|
| Entrez Gene ID: | 820496 |
| Pfam: | PF00664 PF00005 |
| KEGG: | ath:AT3G13080 |
Gene Ontology
GO:0048046
C:apoplast
GO:0016021
C:integral to membrane
GO:0000325
C:plant-type vacuole
GO:0005886
C:plasma membrane
GO:0005774
C:vacuolar membrane
GO:0005524
F:ATP binding
GO:0010290
F:chlorophyll catabolite transmembrane transp...
GO:0015431
F:glutathione S-conjugate-exporting ATPase ac...
GO:0008559
F:xenobiotic-transporting ATPase activity
GO:0055085
P:transmembrane transport
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References (8)[1] “Differential expression of genes coding for ABC transporters after treatment of Arabidopsis thaliana with xenobiotics.” Tommasini R.et.al. 9271206 [2] “Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC clones.” Kaneko T.et.al. 10907853 [3] “Cloning and expression analyses of the AtMRP4, a novel MRP-like gene from Arabidopsis thaliana.” Sanchez-Fernandez R.et.al. 9671034 [4] “An ABC-transporter of Arabidopsis thaliana has both glutathione-conjugate and chlorophyll catabolite transport activity.” Tommasini R.et.al. 9681016 | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MDFLGSTTGS GTLAMLFSFS ESILPLDSRS FLLKPLFLRW LSGFLHSVLL LVLFFSWVRK 61: KIRGDSGVTE SLKDRRDFGF KSALFCSLAL SLLNLVLMSL SGFYWYESGW LDNEQLVSSL 121: GFLLGMVSWG VLSICLHRCR DCEHKKAPFL LRLWLVFYLV VSCYSLVVDF VMYERRETVP 181: VHLLVFDIVA FIAAVFLGYV AVLKKDRSNS NGVLEEPLLN GGDSRVGGDD SVELNKTNGS 241: GEATPYSRAG ILSLLTFSWM SPLIDIGNKK TLDLEDVPQL HDTDSVVGLA PKFRSMLESP 301: DGGERSGVTT FKLIKALYFT AQWEILVTAF FAFIYTVASY VGPALIDTFV QYLNGRRQYN 361: HEGYVLVITF FAAKIVECLS QRHWFFRLQK VGIRMRSALV AMIYEKGLTL SCQSKQGRTS 421: GEIINFMTVD AERIGNFSWY MHDPWMVLLQ VGLALWILYR NLGLASIAAL VATIIVMLIN 481: FPFGRMQERF QEKLMEAKDS RMKSTSEILR NMRILKLQGW EMKFLSKIFD LRKSEEGWLK 541: KYVYNSAVIS FVFWGAPTLV SVSTFGACIL LGIPLESGKI LSALATFRIL QEPIYNLPDT 601: ISMIVQTKVS LDRLASYLCL DNLQPDIVER LPKGSSDVAV EVINSTLSWD VSSSNPTLKD 661: INFKVFPGMK VAVCGTVGSG KSSLLSSLLG EVPKVSGSLK VCGTKAYVAQ SPWIQSGKIE 721: DNILFGKPME RERYDKVLEA CSLSKDLEIL SFGDQTVIGE RGINLSGGQK QRIQIARALY 781: QDADIYLFDD PFSAVDAHTG SHLFKEVLLG LLCSKSVIYV THQVEFLPAA DLILVMKDGR 841: ISQAGKYNDI LNSGTDFMEL IGAHQEALAV VDSVDANSVS EKSALGQENV IVKDAIAVDE 901: KLESQDLKND KLESVEPQRQ IIQEEEREKG SVALDVYWKY ITLAYGGALV PFILLGQVLF 961: QLLQIGSNYW MAWATPVSED VQAPVKLSTL MIVYVALAFG SSLCILLRAT LLVTAGYKTA 1021: TELFHKMHHC IFRSPMSFFD STPSGRIMSR ASTDQSAVDL ELPYQFGSVA ITVIQLIGII 1081: GVMSQVSWLV FLVFIPVVAA SIWYQRYYIA AARELSRLVG VCKAPLIQHF SETISGATTI 1141: RSFSQEFRFR SDNMRLSDGY SRPKFYTAGA MEWLCFRLDM LSSLTFVFSL VFLVSIPTGV 1201: IDPSLAGLAV TYGLSLNTLQ AWLIWTLCNL ENKIISVERI LQYASVPSEP PLVIESNRPE 1261: QSWPSRGEVE IRDLQVRYAP HMPLVLRGIT CTFKGGLRTG IVGRTGSGKS TLIQTLFRIV 1321: EPSAGEIRID GVNILTIGLH DLRLRLSIIP QDPTMFEGTM RSNLDPLEEY TDDQIWEALD 1381: KCQLGDEVRK KEQKLDSSVS ENGDNWSMGQ RQLVCLGRVL LKRSKILVLD EATASVDTAT 1441: DNLIQKTLRE HFSDCTVITI AHRISSVIDS DMVLLLSNGI IEEYDTPVRL LEDKSSSFSK 1501: LVAEYTSRSS SSFD