3.A.1.208.25
The ABC-thiol (cysteine; glutathione) exporter, MrpA (Mukherjee et al., 2007). 83% identical to 3.A.1.208.6.
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| Accession Number: | E9BG49 |
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| Protein Name: | ABC-thiol transporter |
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| Length: | 1347 |
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| Molecular Weight: | 149552.00 |
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| Species: | Leishmania donovani (strain BPK282A1) [981087] |
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| Number of TMSs: | 9 |
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| Substrate |
glutathione, cysteine |
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1: MATPDFVRLS PTDESSELII HAPSQRCHTR CGAENGHTTS IITDLEAVDD VAQVRCQQQA
61: QREFAEQLDE LWGSEPTYTP TVEDQASWLQ QLHYGWIGDY IYKAATGSIT EADLPPPSRS
121: TRTYHTGRKL SRQAHADIDA SRRWDGYVGC EVMYEAEAET SGALRWVGYL QQSDYPRSLV
181: AGVEWRVPPR YRRQATPGSA AGLHNGVVHG ERLFRPYEDN YLCSCEPVER LYLSSTCSLM
241: RPGPPPSPDL LFTLFKAHSY HVWAQILPKL LADVTALMLP VLLEYFVKYL DADNATWGWG
301: LGLVLTLFLT NVIQSCAAHK YDHISIRSAA LFETSSMALL FEKCFTVSQR SLQRPDMSVG
361: RIMNMVGNDV DNIGSLNWYV MYFWSAPLQL TLCMLLLIRL VGWFALPGMA VLLVTLPLQG
421: AISKHVQEVS ERMASVVDLR IKRTSELLSG ARIVKFMGWE PVFLARIEDA RSRELQCLRD
481: VHLANVIFMF VNDATPTLVV AVVFILYHAS GQALRPEIVF PTIALLNTMR VSFFMIPLIV
541: SAILQCLVST KRVTTFVECP DTRSQVRDIA GIDAAGAAAI FKDVSIHTYL PAKLPQCKSR
601: LTTMQRITLW FRRRGVPEAE WYDLDGPDAG ASSPTVHLPT LDMGSAQTAS ADGDGAATGG
661: GDEEGDVEER VAQYYQLVPK ELLRNVNLVI PQFKLTMVIG ATGSGKSTLL GSLMGEYDVQ
721: SGEVWAERSI AYVPQQAWIM NATVRDNILF FDEERAADLQ DVIRCCQLEA DLAQLGGGLE
781: TEIGEMGVNL SGGQKARVSL ARAVYANRDV YLLDDPLSAL DAHVGQRVVQ DVIRGRLHGK
841: TRVLATHQIH LLPLADYIVV LQRGRIAFAG DYAAFAATSL EETLRGELKE NKDAESRGSD
901: ADAEAARAET APDIAEAHEP KVEQETSLAG GEDPLRSDVE AGRLMTREEK ATGQVPWSTY
961: VAYLRSCGGL AAWGFLLATF AVTESVTAAN GVWLSIWSTG SLRCSAATYL YVYLFIVFLN
1021: IFNSPLRCFL CYYLMRMGSR NLHRDLLESI GVARMSFFDT TPLGRVLNRF TKDMGILDNT
1081: LNDSYLYLLQ YFFSMCSKVI ILSAAQPFVL VAIVPCVFIY YKLMQIYSAS NRETRRIKSI
1141: AHSPVFTLLE ESLQGQRTIA TYGKMHLVLQ EALRRLDVVY SALYMQNVSN RWLGVRLEFV
1201: SCVITFVVAL IGVIGKMERA SSQSIGLISL SLTMAITLTE TLNWLVRQVA TVEANMNSVE
1261: RVMYYTHEVE HEYVPEMKEL VAQLVGSESG TAAEVTGTVV IEPASPTSAA PHTVQAGSLV
1321: FEGVQMRYRE GLPLVLRGVS FRIAPRE