3.A.1.208.28
Vacuolar iron transporter, Abc3(+) of 1465 aas. Induced by low iron and repressed by high iron. Required for growth in a low iron medium. Probably mobilizes stored vacuolar iron (Pouliot et al. 2010).
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| Accession Number: | Q9P5N0 |
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| Protein Name: | ATP-binding cassette transporter abc3 |
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| Length: | 1465 |
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| Molecular Weight: | 166613.00 |
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| Species: | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) [284812] |
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| Number of TMSs: | 12 |
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| Location1 / Topology2 / Orientation3: |
Vacuole membrane1 / Multi-pass membrane protein2 |
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| Substrate |
iron(3+) |
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1: MITANKGLSL VLLIPNLFAL VSGGLQYVFD VRRRIFRPHF SQFWTIWMKF FSIALVIITQ
61: IYVGYKTKNI GWNFFSVVTY CFVLFLQFAE QSTLRVPMAS LLIFWLLKVV TSLLILLFSP
121: YIAITSMARL LTLITLFCSL VCFISEVYVP PCNRVWYSDD TNEVEEKGIR PSEVRYANIF
181: SKLSFSWISS FIKFGYTNYL KESDVWLLPP DERSGNLIIG FEDWWIYHSK NKRRSLFLWK
241: LLFFNHWKLV ALITITKLIQ DVLAFVQPTL IQKTILFISS YTSPNPESPS RGFIIAILVL
301: VANFLQTLLL QQYNQLIMLL GMRWKTELLA SIYRKSLLLS SSARQNRSIG DIINYMAVDT
361: QKISDLPIYL FIIVSGPFQI ALALSNLYHL MGYSAFTGVA ASVILFPCNI IVANVYKKFQ
421: SILMKNKDSR SKLMTEIINN IRSIKLYAWE TPFLQKLLHI RNTKELSMLK KIGFITAIGD
481: FAWIFTTIIV TTVAFGAFII FHGKTQALTA DIVFPAVSLF NLLQFPLAML PTVISSLLEA
541: SVSVSRIYEF LIAQELDYNG VQRFPATEIP HEICLEIKSG TFSWSKKTLK QQVTPTLRQI
601: NFVAKNGELT CIFGKVGAGK SSLLEACMGN MYKNSGSVFQ CGSLAYAAQQ PWIFDATIRE
661: NILFGSEFDP ELYEKTIHAC CLKRDFEIFT EGDQTEVGQK GASLSGGQKS RISLARAIYS
721: QADIYLLDDV LSSVDQHVSR DLIKNLFGPE GFLRTHCVVL TTNSLNVLKE ADSIYILSNG
781: KIVEKGNYEH LFVSTNSELK QQLSEFNDEK DTQPLPEHTT SYPSTQISLA PSIHVEGLET
841: YSSSERKDSS NKYKSRKRNP IRQKVTEDDK GKCVAQTDEL VQRGKVKWHV YWMYFKSCSI
901: GLILLYFFFI ISGIMMNVAT NVWLKHWSEE NGKSSSELNP SPYFYLGIYL FFGFLSCAFI
961: SSSSLTMTVL CGIRSGRYLH DSMLKTILRA PMGFFETTSS GRILNRFSND VYKVDEVVSL
1021: TFMFFFRNSI QVLFILGVIC YSAPLSLLLI VPLFFLYLYN RAYYVRTSRE LKRLDNVTRS
1081: PLYAHVQESL SGLSTIRAYG MQETFVEEND LRIDTNHRVW FMFFSSSRWQ AIRVECIGDL
1141: IIFCTAFYGI LSAIKGSPNP GLVGFSLSYA IQITQGLSFI VQQSVDAENN TVSVERILEY
1201: INVKSEAPEI IPENRPPCEW PTDGAVSFNH YSAKYREDLS FALNNINIEI SPREKIGIVG
1261: RTGAGKSTLA MALFRIIEPT EGKIEIDNED ITKFGLYDLR SRLSIIPQES QIFEGNIREN
1321: LDPNHRLTDK KIWEVLEIAS LKNCISQLED GLYSRVAEGG ANFSSGQRQL ICLARVLLTS
1381: TRILLLDEAT ASVHAETDAI VQQTIRKRFK DRTILTVAHR INTVMDSDRI LVLDHGKVVE
1441: FDATKKLLEN KDSMFYSLAK ESGLI