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| Accession Number: | P53049 |
| Protein Name: | YOR1 aka YGR281W |
| Length: | 1477 |
| Molecular Weight: | 166728.00 |
| Species: | Saccharomyces cerevisiae (Baker's yeast) [4932] |
| Number of TMSs: | 12 |
| Location1 / Topology2 / Orientation3: | Membrane1 / Multi-pass membrane protein2 |
| Substrate | tetracycline, ethidium bromide, eosin YS dye, lissamine rhodamine, verapamil, oligomycin |
Cross database links:
| DIP: | DIP-6796N |
|---|---|
| RefSeq: | NP_011797.1 |
| Entrez Gene ID: | 853198 |
| Pfam: | PF00664 PF00005 |
| KEGG: | sce:YGR281W |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0005624
C:membrane fraction
GO:0005886
C:plasma membrane
GO:0005524
F:ATP binding
GO:0042802
F:identical protein binding
GO:0008559
F:xenobiotic-transporting ATPase activity
GO:0042493
P:response to drug
GO:0055085
P:transmembrane transport
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References (10)[1] “Expression of an ATP-binding cassette transporter-encoding gene (YOR1) is required for oligomycin resistance in Saccharomyces cerevisiae.” Katzmann D.J.et.al. 8524254 [2] “Sequence analysis of a near-subtelomeric 35.4 kb DNA segment on the right arm of chromosome VII from Saccharomyces cerevisiae carrying the MAL1 locus reveals 15 complete open reading frames, including ZUO1, BGL2 and BIO2 genes and an ABC transporter gene.” Volckaert G.et.al. 9090054 [3] “The nucleotide sequence of Saccharomyces cerevisiae chromosome VII.” Tettelin H.et.al. 9169869 [4] “A general strategy to uncover transcription factor properties identifies a new regulator of drug resistance in yeast.” Hikkel I.et.al. 12529331 [5] “Global analysis of protein expression in yeast.” Ghaemmaghami S.et.al. 14562106 [6] “Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.” Gruhler A.et.al. 15665377 | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MTITVGDAVS ETELENKSQN VVLSPKASAS SDISTDVDKD TSSSWDDKSL LPTGEYIVDR 61: NKPQTYLNSD DIEKVTESDI FPQKRLFSFL HSKKIPEVPQ TDDERKIYPL FHTNIISNMF 121: FWWVLPILRV GYKRTIQPND LFKMDPRMSI ETLYDDFEKN MIYYFEKTRK KYRKRHPEAT 181: EEEVMENAKL PKHTVLRALL FTFKKQYFMS IVFAILANCT SGFNPMITKR LIEFVEEKAI 241: FHSMHVNKGI GYAIGACLMM FVNGLTFNHF FHTSQLTGVQ AKSILTKAAM KKMFNASNYA 301: RHCFPNGKVT SFVTTDLARI EFALSFQPFL AGFPAILAIC IVLLIVNLGP IALVGIGIFF 361: GGFFISLFAF KLILGFRIAA NIFTDARVTM MREVLNNIKM IKYYTWEDAY EKNIQDIRTK 421: EISKVRKMQL SRNFLIAMAM SLPSIASLVT FLAMYKVNKG GRQPGNIFAS LSLFQVLSLQ 481: MFFLPIAIGT GIDMIIGLGR LQSLLEAPED DPNQMIEMKP SPGFDPKLAL KMTHCSFEWE 541: DYELNDAIEE AKGEAKDEGK KNKKKRKDTW GKPSASTNKA KRLDNMLKDR DGPEDLEKTS 601: FRGFKDLNFD IKKGEFIMIT GPIGTGKSSL LNAMAGSMRK TDGKVEVNGD LLMCGYPWIQ 661: NASVRDNIIF GSPFNKEKYD EVVRVCSLKA DLDILPAGDM TEIGERGITL SGGQKARINL 721: ARSVYKKKDI YLFDDVLSAV DSRVGKHIMD ECLTGMLANK TRILATHQLS LIERASRVIV 781: LGTDGQVDIG TVDELKARNQ TLINLLQFSS QNSEKEDEEQ EAVVAGELGQ LKYESEVKEL 841: TELKKKATEM SQTANSGKIV ADGHTSSKEE RAVNSISLKI YREYIKAAVG KWGFIALPLY 901: AILVVGTTFC SLFSSVWLSY WTENKFKNRP PSFYMGLYSF FVFAAFIFMN GQFTILCAMG 961: IMASKWLNLR AVKRILHTPM SYIDTTPLGR ILNRFTKDTD SLDNELTESL RLMTSQFANI 1021: VGVCVMCIVY LPWFAIAIPF LLVIFVLIAD HYQSSGREIK RLEAVQRSFV YNNLNEVLGG 1081: MDTIKAYRSQ ERFLAKSDFL INKMNEAGYL VVVLQRWVGI FLDMVAIAFA LIITLLCVTR 1141: AFPISAASVG VLLTYVLQLP GLLNTILRAM TQTENDMNSA ERLVTYATEL PLEASYRKPE 1201: MTPPESWPSM GEIIFENVDF AYRPGLPIVL KNLNLNIKSG EKIGICGRTG AGKSTIMSAL 1261: YRLNELTAGK ILIDNVDISQ LGLFDLRRKL AIIPQDPVLF RGTIRKNLDP FNERTDDELW 1321: DALVRGGAIA KDDLPEVKLQ KPDENGTHGK MHKFHLDQAV EEEGSNFSLG ERQLLALTRA 1381: LVRQSKILIL DEATSSVDYE TDGKIQTRIV EEFGDCTILC IAHRLKTIVN YDRILVLEKG 1441: EVAEFDTPWT LFSQEDSIFR SMCSRSGIVE NDFENRS