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| Accession Number: | Q42093 |
| Protein Name: | ABC transporter C family member 2 |
| Length: | 1623 |
| Molecular Weight: | 182130.00 |
| Species: | [3702] |
| Number of TMSs: | 15 |
| Location1 / Topology2 / Orientation3: | Vacuole membrane1 / Multi-pass membrane protein2 |
| Substrate | glutathione, 17beta-estradiol, red chlorophyll catabolite(2-), glutathione conjugate, 1-chloro-2,4-dinitrobenzene, drug |
Cross database links:
| RefSeq: | NP_181013.1 |
|---|---|
| Entrez Gene ID: | 818031 |
| Pfam: | PF00664 PF00005 |
| KEGG: | ath:AT2G34660 |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0000325
C:plant-type vacuole
GO:0005886
C:plasma membrane
GO:0005774
C:vacuolar membrane
GO:0005524
F:ATP binding
GO:0005516
F:calmodulin binding
GO:0008559
F:xenobiotic-transporting ATPase activity
GO:0055085
P:transmembrane transport
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References (10)[1] “Cloning of AtMRP1, an Arabidopsis thaliana cDNA encoding a homologue of the mammalian multidrug resistance-associated protein.” Marin E.et.al. 9528668 [2] “AtMRP2, an Arabidopsis ATP-binding cassette transporter able to transport glutathione S-conjugates and chlorophyll catabolites: functional comparisons with AtMRP1.” Lu Y.-P.et.al. 9490749 [3] “Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.” Lin X.et.al. 10617197 [4] “Differential expression of genes coding for ABC transporters after treatment of Arabidopsis thaliana with xenobiotics.” Tommasini R.et.al. 9271206 [5] “Enhanced multispecificity of Arabidopsis vacuolar multidrug resistance-associated protein-type ATP-binding cassette transporter, AtMRP2.” Liu G.et.al. 11115509 [6] “The Arabidopsis thaliana ABC protein superfamily, a complete inventory.” Sanchez-Fernandez R.et.al. 11346655 | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MGFEFIEWYC KPVPNGVWTK QVANAFGAYT PCATDSFVLG ISQLVLLVLC LYRIWLALKD 61: HKVERFCLRS RLYNYFLALL AAYATAEPLF RLIMGISVLD FDGPGLPPFE AFGLGVKAFA 121: WGAVMVMILM ETKIYIRELR WYVRFAVIYA LVGDMVLLNL VLSVKEYYSS YVLYLYTSEV 181: GAQVLFGILL FMHLPNLDTY PGYMPVRSET VDDYEYEEIS DGQQICPEKH ANIFDKIFFS 241: WMNPLMTLGS KRPLTEKDVW YLDTWDQTET LFTSFQHSWD KELQKPQPWL LRALNNSLGG 301: RFWWGGFWKI GNDCSQFVGP LLLNQLLKSM QEDAPAWMGY IYAFSIFVGV VFGVLCEAQY 361: FQNVMRVGYR LRSALIAAVF RKSLRLTNEG RRKFQTGKIT NLMTTDAESL QQICQSLHTM 421: WSAPFRIIIA LILLYQQLGV ASLIGALLLV LMFPLQTVII SKMQKLTKEG LQRTDKRIGL 481: MNEVLAAMDT VKCYAWENSF QSKVQTVRDD ELSWFRKSQL LGALNMFILN SIPVLVTIVS 541: FGVFTLLGGD LTPARAFTSL SLFAVLRFPL FMLPNIITQV VNANVSLKRL EEVLATEERI 601: LLPNPPIEPG EPAISIRNGY FSWDSKGDRP TLSNINLDVP LGSLVAVVGS TGEGKTSLIS 661: AILGELPATS DAIVTLRGSV AYVPQVSWIF NATVRDNILF GSPFDREKYE RAIDVTSLKH 721: DLELLPGGDL TEIGERGVNI SGGQKQRVSM ARAVYSNSDV YIFDDPLSAL DAHVGQQVFE 781: KCIKRELGQK TRVLVTNQLH FLSQVDRIVL VHEGTVKEEG TYEELSSNGP LFQRLMENAG 841: KVEEYSEENG EAEADQTAEQ PVANGNTNGL QMDGSDDKKS KEGNKKGGKS VLIKQEERET 901: GVVSWRVLKR YQDALGGAWV VMMLLLCYVL TEVFRVTSST WLSEWTDAGT PKSHGPLFYN 961: LIYALLSFGQ VLVTLTNSYW LIMSSLYAAK KLHDNMLHSI LRAPMSFFHT NPLGRIINRF 1021: AKDLGDIDRT VAVFVNMFMG QVSQLLSTVV LIGIVSTLSL WAIMPLLVLF YGAYLYYQNT 1081: AREVKRMDSI SRSPVYAQFG EALNGLSTIR AYKAYDRMAD INGRSMDNNI RFTLVNMGAN 1141: RWLGIRLETL GGLMIWLTAS FAVMQNGRAE NQQAFASTMG LLLSYALNIT SLLTGVLRLA 1201: SLAENSLNAV ERVGNYIEIP PEAPPVIENN RPPPGWPSSG SIKFEDVVLR YRPQLPPVLH 1261: GVSFFIHPTD KVGIVGRTGA GKSSLLNALF RIVEVEKGRI LIDDCDVGKF GLMDLRKVLG 1321: IIPQSPVLFS GTVRFNLDPF GEHNDADLWE SLERAHLKDT IRRNPLGLDA EVSEAGENFS 1381: VGQRQLLSLS RALLRRSKIL VLDEATAAVD VRTDALIQKT IREEFKSCTM LIIAHRLNTI 1441: IDCDKILVLD SGRVQEFSSP ENLLSNEGSS FSKMVQSTGA ANAEYLRSLV LDNKRAKDDS 1501: HHLQGQRKWL ASSRWAAAAQ FALAASLTSS HNDLQSLEIE DDSSILKRTN DAVVTLRSVL 1561: EGKHDKEIAE SLEEHNISRE GWLSSLYRMV EGLAVMSRLA RNRMQQPDYN FEGNTFDWDN 1621: VEM