3.A.1.208.50
ABC transporter C family member 4, ABCC4, of 1495 aas and 17 TMSs in a 5 + 6 (2 + 2 + 2) + 6 (2 + 2 + 2 TMS arrangement (M + M + C + M + C overall domain order). In Crocus sativus, it transports Apocarotenoid; in saffrom stigmas, crocins, it transports a mixture of apocarotenoid glycosides (Demurtas et al. 2020). Apocarotenoids are carotenoid derivatives produced by the nonenzymatic or enzymatic cleavage of carotenoids, followed by different enzymatic modifications. In plants, apocarotenoids play various roles, such as attraction of pollinators and seeds dispersal, defense against pathogens and herbivores, protection against photo-oxidative stresses, stimulation and inhibition of plant growth and regulation of biological processes in the case of phytohormones abscisic acid and strigolactones. While carotenoids are in general plastid-localized metabolites, apocarotenoids can reach different final destinations inside or outside the cell (Demurtas et al. 2020).
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| Accession Number: | PKU85821.1 |
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| Protein Name: | PKU85821.1 ABC transporter C family member 4 [Dendrobium catenatum] |
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| Length: | 1496 |
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| Molecular Weight: | |
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| Species: | Dendrobium catenatum [906689] |
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| Number of TMSs: | 20 |
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| Substrate |
apo carotenoid |
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1: MSFSISAFTC SPPPGATVGK LLYFVFLSPC PQRALFSLLD LLFLLTLLLF VIQKLLSRRH
61: ESNSDAAKPL LPTSSAVRTT WRFNLPLAIS SILAAAFLVL LVLALALDKS SPFSWRLLQS
121: IFFSFQFLSH LAAAAVIAHE KRFRAISHPL TLRLFWIFSF LLSILLTVSA VLRLFSSSAN
181: FPDGIASLVF LLFSAALLVF ALSPSTGFHS QLSSSSPSST GDSNLSEDSE SKPNVTAYTT
241: ASLLSRLTWS WMNPLLAKGY KSPLKLQDVP SLAPEHQAQR LYNLFNSHWP RPAIKSHHPV
301: RTTLLRCFWP QLLLTASLAV LRLCVMYVGP TLINRFIDFA SGRRSSIYEG YYLCLTLLAA
361: KFVEVLCSHH YNFHSQKTGM LIRSTLITTL YRKGLRLSCS ARQSHGLGMI VNYMAVDAQQ
421: LSDMMLQIHY IWLMPLQVGV ALALLYVYLG PSVTSAVVGI IAVMVFVVFG TRRNNLFQFS
481: LMGMRDKRMK ATNEMLNYMR VIKFQAWEEH FNKRIQGFRS EEFGWLSRFM YSISGNIIVL
541: WSAPLVISSL VFGTCIAAGV RLDAGIVFTA TSFFKILQEP MRNFPQALIS ASQAMISLER
601: LDAYMTSGEL DEGAVEQVLS GYAVDAPAVE VCEGTFGWED DVSADTAWLK RVNVRIPRGA
661: VAAVVGTVGS GKSSFLSCLV GEMHRISGKV RVCGSMAYVA QTAWIQNGTI QDNILFGLPL
721: NQQKYKEVIR VCCLTKDLEM MEFGDQTEIG ERGINLSGGQ KQRIQLARAV YQDSDVYLLD
781: DVFSAVDAHT GSEIFKECIR GALKDKTVIL VTHQVDFLHN ADLILVMRDG MIVQSGKYNE
841: ILNAGADFAA LVAAHDSSME LVEHGPPEQV RMDSPSKQGD QTITNDEKSK DESSVISPKT
901: EKSSAKLIKD EERETGKVSL NVYKTYITEA WGWWGVIAVL IVSLLWQGSL MASDYWLALS
961: TSANNASSFN PSQFIEVYVI IAVISVILVA GRSFLVTYWG LKTAQIFFKQ ILNSILHAPM
1021: SFFDTTPSGR ILSRASSDQT NVDLFLPFFV GLTVSMYITV LSILIVTIQV AWPTLFFIIP
1081: LAWLNVWYRG YYLTTSRELT RLDSITKAPV IHHFSETIQG VMTIRCFKKE ERFSQENINR
1141: VNASLTMDFH NNGSNEWMGF RLELIGTVIL CISALSMVML PSNFIKPEYV GLSLSYGLSL
1201: NSVLFWAIWI SCFLENRMVS VERLKQFSSI PPEAPWRIKD RLPSPNWPTH GDIILRDLKV
1261: RYRPNTPLVL HGITLDIHGG EKIGVVGRTG SGKSTLIQAL FRIVEPSGGK IIIDGIDICI
1321: LGLHDLRSRF GIIPQEPVLF EGTVRSNVDP VGQYTDDEIW QSLERCQLKQ AVAAKPEKLD
1381: ALVVDNGENW SVGQRQLFCL GRVLLKKSRI LFMDEATASV DSQTDGFIQK IIREDFSNCT
1441: IISIAHRIPT VMDCDRVLVV DSGLAKEFDS PTNLIERPSL FGALVQEYAN RSSDL