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| Accession Number: | Q25693 |
| Protein Name: | Pfmdr2 |
| Length: | 1025 |
| Molecular Weight: | 119153.00 |
| Species: | Plasmodium falciparum [5833] |
| Number of TMSs: | 9 |
| Location1 / Topology2 / Orientation3: | Mitochondrion inner membrane1 / Multi-pass membrane protein2 |
| Substrate | cadmium(2+), drug |
Cross database links:
| Pfam: | PF00664 PF00005 |
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Gene Ontology
GO:0016021
C:integral to membrane
GO:0005524
F:ATP binding
GO:0042626
F:ATPase activity, coupled to transmembrane m...
GO:0055085
P:transmembrane transport
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References (1)[1] “Plasmodium falciparum: the pfmdr2 protein is not overexpressed in chloroquine-resistant isolates of the malaria parasite.” Rubio J.P.et.al. 7914495
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External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MDVSNYEYLR SYGIKNELKR KRTHKKIIIY HLLDIIIFFL LFFSCYNFNL ELCYKYEKAI 61: FYNFFKSSVD LFLLNVIRII YTVILFRLHK KLTELNTLGK VYVLSRHITG ILVILNVIKM 121: INYSYVIKSE NPLYNTNMYL ITLKVLFMVY SMISSIYYYF IQFKLYNIKK KYIIARVELE 181: KILINDIKSK KYNIYKSDEN SGLLGTDNNS TIMNNEYLNL DYKNLLDMNI SYNKLNEKIN 241: NDIINNTSDV QEKNMDYNDI HNFQKKKKSS NFAYLNFFHK ESKDNKIDVK ESFLNKRYGS 301: NKRSSKIYDN NNNNNNNNNI NSKIDYLENN ITYTEFKKIL LPYLWPSKRI DMKGNSSILR 361: TYIVLIFLFI LVSKVFSVIS PIYLGWASNE VLKKSLSSSV YYLGLYVTFF FISKFLKEVC 421: GVLFSQVQQS AFIELQESIF QTFHNLSYEW YSSKNSGGIM RIVDRGTESA NNLMSSVLMY 481: IIPATIEGLI TCIIFIFKYK NSLLGSVLFI GLTLYIYSTI KITKWRKKIR TKANEMDNVY 541: HDIAHDSLTN YENVKYFSNE KFEIKKFCNA LSNYHRYNLK ILNSLGILNT VQQFILNGTL 601: FFTLLCVIYM IVKEGSDPGT FISVVVYTSN VFAPLSILGT LYATIIKSFT DISDLIDILR 661: DKIDISNDKN LKNFDLTSQE KKFGVSIEFN NVHFNYPTQP LHTSLKDINI YIKPGTTCAL 721: VGHTGSGKTT ISKLLYRFYD SKGEIKIGGR NINEYTRNSI RNIIGIVPQD TILFNESIKY 781: NILYGKLDAT EEELIQAVKS AQLYDFIQSL PKKWDTLVGD KGVKLSGGER QRISIARCLL 841: KDPKIVIFDE ATSSLDSRTE YLFQKAVEDL RKNRTIIIIA HKLCTITTAE LIILLNKGKI 901: IERGTHLDLL KCNGEYTEMW NMQSKSNEPH TETNSSIDKD DVNKNNNKNN DVILNTCKND 961: ITTSFRSNSE KSSQEFSDAS NHIKQSKTSN DHNNNINVHK KNEQEQLFLT NDKTDMDDNM 1021: NNKKK