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3.A.1.3.13
Uptake system for L-cystine (Km=2.5 μM), L-cystathionine, L-djenkolate ( 2-amino-3-[(2-amino-3-hydroxy-3-oxopropyl)sulfanylmethylsulfanyl] propanoic acid), and S-methyl-L-cysteine (Burguière et al., 2004, Burguière et al., 2005)

Accession Number:O34900
Protein Name:TcyN (YtmN)
Length:259
Molecular Weight:29562.00
Species:Bacillus subtilis [1423]
Location1 / Topology2 / Orientation3: Cell membrane1 / Peripheral membrane protein2
Substrate S-methylcysteine, cystathionine, L-djenkolic acid

Cross database links:

RefSeq: NP_390812.1   
Entrez Gene ID: 937364   
Pfam: PF00005   
KEGG: bsu:BSU29340   

Gene Ontology

GO:0005886 C:plasma membrane
GO:0005524 F:ATP binding
GO:0016887 F:ATPase activity
GO:0006865 P:amino acid transport

References (4)

[1] “Sequencing and functional annotation of the Bacillus subtilis genes in the 200 kb rrnB-dnaB region.”  Lapidus A.et.al.   9387221
[2] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377
[3] “Global expression profile of Bacillus subtilis grown in the presence of sulfate or methionine.”  Auger S.et.al.   12193636
[4] “Three different systems participate in L-cystine uptake in Bacillus subtilis.”  Burguiere P.et.al.   15262924

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MIEIKNIHKQ FGIHHVLKGI NLTVRKGEVV TIIGPSGSGK TTFLRCLNLL ERPDEGIISI 
61:	HDKVINCRFP SKKEVHWLRK QTAMVFQQYH LFAHKTVIEN VMEGLTIARK MRKQDAYAVA 
121:	ENELRKVGLQ DKLNAYPSQL SGGQKQRVGI ARALAIHPDV LLFDEPTAAL DPELVGEVLE 
181:	VMLEIVKTGA TMIVVTHEME FARRVSDQVV FMDEGVIVEQ GTPEEVFRHT KKDRTRQFLR 
241:	RVSPEYLFEP KEHIKEPVI