3.A.1.4.3
General L- (and D-)amino acid uptake porter (transports acidic, basic, polar, semipolar and hydrophobic amino acids). The amino and carboxyl groups do not need to be α since γ-aminobutyric acid (GABA) is a substrate. The system may function with additional binding proteins since L-alanine uptake is not dependent on BraC.
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| Accession Number: | Q8VM83 |
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| Protein Name: | BraF aka Bra2F |
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| Length: | 257 |
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| Molecular Weight: | 28087.00 |
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| Species: | Rhizobium leguminosarum (biovar viciae) [387] |
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| Number of TMSs: | 1 |
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| Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
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| Substrate |
alpha-amino acid, gamma-aminobutyric acid |
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| Pfam: |
PF00005
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[1] “Rhizobium leguminosarum has a second general amino acid permease with unusually broad substrate specificity and high similarity to branched-chain amino acid transporters (Bra/LIV) of the ABC family.” Hosie A.H. et.al. 12107123
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1: MTSHLPLLEI KNLSKSYGAV KAVNDVSIHI DRGEIAGLIG PNGSGKSTFF DCSTGLAKPD
61: TGTVVLDGQD ITGWSLNRIA REGRMLRSFQ KTVTFRSLDV EENLVIAGQM FTFPSITSTF
121: GLGKMSRQRV GGLRERARDL IKMAGLWDVR HQPAGNLSGG QQKLIQFASM LMPEPKLILL
181: DEPMAGINPK IIERVVDTIR YANKSLGVSF LVIEHNIDVV TSICQRVIVL DQGAKLVEGL
241: PGDIIQDQRV REAYLGG