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3.A.1.4.3
General L- (and D-)amino acid uptake porter (transports acidic, basic, polar, semipolar and hydrophobic amino acids). The amino and carboxyl groups do not need to be α since γ-aminobutyric acid (GABA) is a substrate. The system may function with additional binding proteins since L-alanine uptake is not dependent on BraC.

Accession Number:Q8VM84
Protein Name:BraE aka Bra2E
Length:331
Molecular Weight:35387.00
Species:Rhizobium leguminosarum (biovar viciae) [387]
Number of TMSs:9
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate alpha-amino acid, gamma-aminobutyric acid

Cross database links:

Pfam: PF02653   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0006810 P:transport

References (1)

[1] “Rhizobium leguminosarum has a second general amino acid permease with unusually broad substrate specificity and high similarity to branched-chain amino acid transporters (Bra/LIV) of the ABC family.”  Hosie A.H.et.al.   12107123

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSLTETAQQA RRRDLRIPLA AVLVVLALAA PFIGSRYITH SLIIALIFML PAHGLNLLVG 
61:	YTGLLSLAQA AFFGIGAYTA GLLAVTYGTP FYVNLIAAGA VSGPVALPLG IPALRLRSTS 
121:	FVMCTLGFVI IGQAIAKNWV SLTRGDMGLS SIPKPYFELG PLSFTVSGTT NFYYLALIIG 
181:	TLATFAVWAI VRSPAGRNMV AIRENETLAE SLGVPTWHYK LIVFMISAVF AGVGGCLYAY 
241:	YLTVVSPLTF QMYYSTTMLI IVLGGGAGMI SGTVFGSLLF VGLTEALRIT PELRMIAYGV 
301:	CLLVLVFWFK KGCAPLINRF WNAIDAIGGA K