3.A.10.1.11
The K+-stimulated H+, Na+-PPase. Transports both Na+ and H+ noncompetitively in a single catalytic cycle (Luoto et al., 2013a, b).
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| Accession Number: | E7RS29 |
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| Protein Name: | Putative K(+)-stimulated pyrophosphate-energized sodium pump |
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| Length: | 733 |
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| Molecular Weight: | 76775.00 |
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| Species: | Prevotella oralis ATCC 33269 [873533] |
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| Number of TMSs: | 16 |
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| Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
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| Substrate |
sodium(1+), hydron |
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1: MNIPIVFWLV PIASIIALSM AWFFFSTMMK EDEGLPRMRE IALYVRKGAM TYLKQQYKVV
61: LYVFIVIAII FAFMAYVLKV QNPWVPFAFL TGGLFSGLAG FFGMKTATYA SGRTANAARS
121: GLDRGLKIAF RSGAVMGLVV VGLGLLDIAI WFLILNAFYS GEQTSLITIT TTMLTFGMGA
181: STQALFARVG GGIYTKAADV GADLVGKVEA DIPEDDPRNP ATIADNVGDN VGDVAGMGAD
241: LYESYCGSIL STAALGATAF AMNGEMQLRA VIAPMIIAAV GIFLSLIGIF LVRTKEGAGM
301: KELLHSLGFG TNVSAILIAI ATFIILYLLN MENWMGLSFS VISGLLAGVI IGQSTEYYTS
361: QTYKPTQKIA EASQTGSATV IIKGIGTGMI STCIPVVVIS VAIMMSYLCA NGFNMSMSAQ
421: SISRGLYGIG IAAVGMLSTL GITLATDAYG PIADNAGGNA EMSGLGEDIR KRTDALDALG
481: NTTAATGKGF AIGSAALTAL ALLASYIEEI KIAMIRAVEQ GEQFISAAGT VFDPKSATMT
541: DFMQFFQVNL INPKVLVGAF IGAMAAYLFC GLTMGAVGRA AGAMVSEVRR QFKEIKGILE
601: GKATPDYGRC VEISTQSAQR EMVLPSLLAI IIPIIVGIVL GVAGVLGLLT GGLAAGFTLA
661: IFMANSGGAW DNAKKMVEEG NFGGKGSACH KATIVGDTVG DPFKDTSGPS LNILIKLMSM
721: VSIVMAGLTV AFI