3.A.10.1.12
The K+-stimulated H+, Na+-PPase. Transports both Na+ and H+ noncompetitively in a single catalytic cycle (Luoto et al., 2013a, b).
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| Accession Number: | B5JQT8 |
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| Protein Name: | Putative K(+)-stimulated pyrophosphate-energized sodium pump |
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| Length: | 715 |
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| Molecular Weight: | 74125.00 |
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| Species: | Verrucomicrobiae bacterium DG1235 [382464] |
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| Number of TMSs: | 16 |
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| Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
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| Substrate |
sodium(1+), hydron |
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1: MTPKLFWIAP GSALIGLLFA FLFFRQMTKQ NEGSARMREI AGYVSEGARA YLKQQYKVVT
61: FAFIVLAILF AILAYALHAQ NPWTPVIFVS GGLLSGLSGY FGMKTATASA SRTAQAASES
121: LDRGLRVAFR SGAVMGLCVV GLGLLAISIW FVVLTQIHYK EGAPNMPFIT TALLSFGMGA
181: SLQALFARVG GGIYTKAADV GADLVGKVEA GIPEDDPRNP ATIADNVGDF VGDVAGMGAD
241: LYESYCGSIL ATAALGAAAF AYDPELQLQA AVAPMVVAGL GILLSIIGIY LVHAKEGSSQ
301: HALLSALDRG VNFSALGIAA SSAVAIHLFD LPNPWGIWGA IVMGLIAGIA IGKATEYYTS
361: SDFKPTQTIV ANAETGPATV IISGLGTGMI STYVAVLAVS VSIMLSYTFA SGFQLSNMAH
421: GLYGIGFAAV GMLSTLGVTL ATDAYGPIAD NAGGNAEMSG LPPEVRQRTD ALDSLGNTTA
481: AIGKGFAIGS AALTAMALLA SYVFANPNIE SYKNANEMLA NYIQTHELHL LNPRVLIGLF
541: VGGLMAFLFC GLTMNAVGRT AKDMVEEVRR QFKADPGILK GDTVPDYASC VEISTLGAQR
601: EMIVPALIAV IAPVAIGLLF GPAGVVGLLT GGLTTGFVLA VFMANSGGAW DNAKKYIEEG
661: NMGGKGSDAH KAAVIGDTVG DPFKDTSGPS LNILIKLMTM VAIVTAGITL TYSIF