3.A.10.1.13
The K+-stimulated H , Na +-PPase. Transports both Na + and H + noncompetitively in a single catalytic cycle (Luoto et al., 2013a, b).
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| Accession Number: | A7VNH8 |
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| Protein Name: | Putative K(+)-stimulated pyrophosphate-energized sodium pump |
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| Length: | 700 |
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| Molecular Weight: | 72144.00 |
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| Species: | Clostridium leptum DSM 753 [428125] |
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| Number of TMSs: | 16 |
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| Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
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| Substrate |
sodium(1+), hydron |
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1: MDLSILAPVG AVVALLFAFF LSRRVMKADE GTDLMKKIAG AVRKGANAYL KRQYTGVAIF
61: FAVMFVILLI LAIAGFLTPF VPVAFLTGGF FSALSGFIGM KIATYANGRT ANSASKSLNA
121: GLRIAFSAGG VMGFVVVGLG LLDISIWYFF LKFWYSTVDV MQNEAAQVQA ITSAMLTFGM
181: GASSMALFAR VGGGIFTKAA DVGADLVGKV EAGIPEDDPR NPAVIADNVG DNVGDVAGMG
241: ADLYESYVGS IISTAALAVA AGLGFKGVVI PMSMAAIGIL ASIIGTFFVR TKENASQKNL
301: LGSLRLGTWI SAALIAVAAF PLIYFGLGAE KIGFYFAILS GLLAGILIGV VTEYYTSDSY
361: KPTKKLAGTS STGPATVIIG GLSLGMLSTV LPVVIVGASV LVSYFLSGGS DSYNNGLYGV
421: GLSAVGMLAT LGITLATDAY GPVADNAGGI AEMAHMGEEV RKRTDALDSL GNTTAATGKG
481: FAIGSAALTA LALIASYIAE IQVLKPDFNF NLTITNPPVL IGLFIGGVLP FLFAALTMDA
541: VGRCAQKIVV EVRRQFREIK GLMTGEADPD YASCVDICTR SAQREMIAPA IVAVAAPIIV
601: GLILGVNGVA GMLAGATVSG FILAVMMANS GGAWDNAKKY IESGEYGGKG SDNHKAAVVG
661: DTVGDPFKDT SGPSINILIK LLSMVSIVFA SVVLSFSLIK