3.A.10.1.19
Vacuolar H+ importing pyrophosphatase, VP1, of 717 aas and 16 TMSs in an apparent 5 + 6 + 5 TMS arrangement.
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| Accession Number: | Q8IKR1 |
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| Protein Name: | H(+)-exporting diphosphatase |
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| Length: | 717 |
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| Molecular Weight: | 76417.00 |
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| Species: | Plasmodium falciparum (isolate 3D7) [36329] |
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| Number of TMSs: | 16 |
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| Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
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| Substrate |
hydron, diphosphate(4-), diphosphate(4-) |
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1: MDLFYVFLFL PPTIGLIFSI IECIWVSNIN IKGPEDKVEK LEDGDNPVEK MKEIASYIAV
61: GANAFLKKEF QYLAVFIIVF SILLGFFVNS FTAVSFVLGC LTSILCGYIG MKIAVYANVR
121: TTNETWKSLD KGFQVTLNAG TVMGFSLVSF GIIALGLLIF VYKTYVFKNT IPDNQIYKII
181: AGFGLGGSSI ALFSRVGGGI YTKAADVGAD LSGKNEYGIP EDDIRNPACI ADNVGDNVGD
241: MAGMGADLFG SLAESLCAAL VIGSSVISIG EGSPGNAFHC ILFPLLFVSF SVICSMITFY
301: IITYSVKIND KKDVEKSLKY LLLLSTVLQS LAILAIGYVC FPSLVKYNYL KDIHRWKIIV
361: PALVGLWSGL IIGFTTEFYT SYSFSPVQEI AHTQKVSAAT GIIYGLSLGY KSTFIPIICL
421: SATLGISYGL CDIYGIALAA VGMLSTLCIC LTIDAYGPIS DNAGGIAEMA GLPSEVRERT
481: DILDAAGNTT AAIGKGFAIG SAALVAFALF GAYASSANLR HVNILNSWVI IGLLIGAMLP
541: YLFSALTMKS VAIAANSVLN ECLEQFPLIL EGKQKPDYEK CIKISTDASL RQMIVPGLIS
601: VFSPLIIGML MGKYATAGLL IGIILSGIQL AFSSTNSGGA WDNAKKYIES GALGKEHCKG
661: SNAHKNSVIG DTVGDPLKDT SGPSLNILIK LSAITSLVFA NVIATKFTST RGGPIWL