| |
|---|---|
| Accession Number: | Q8ZWI8 |
| Protein Name: | Pyrophosphate-energized proton pump |
| Length: | 721 |
| Molecular Weight: | 75394.00 |
| Species: | [13773] |
| Number of TMSs: | 16 |
| Location1 / Topology2 / Orientation3: | Cell membrane1 / Multi-pass membrane protein2 |
| Substrate | hydron |
Cross database links:
| RefSeq: | NP_559532.1 |
|---|---|
| Entrez Gene ID: | 1465965 |
| Pfam: | PF03030 |
| BioCyc: | PAER178306:PAE1771-MONOMER |
| KEGG: | pai:PAE1771 |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0005886
C:plasma membrane
GO:0009678
F:hydrogen-translocating pyrophosphatase acti...
GO:0004427
F:inorganic diphosphatase activity
GO:0000287
F:magnesium ion binding
GO:0015992
P:proton transport
| |
References (2)[1] “A thermostable vacuolar-type membrane pyrophosphatase from the archaeon Pyrobaculum aerophilum: implications for the origins of pyrophosphate-energized pumps.” Drozdowicz Y.M.et.al. 10556526 [2] “Genome sequence of the hyperthermophilic crenarchaeon Pyrobaculum aerophilum.” Fitz-Gibbon S.T.et.al. 11792869
| |
External Searches:
|
Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
|
|||
1: MNMISYALLG VILGISGVIY AVYLAVWVLR QDPGNEKMRF ISQAIATGAR AYLFRQYRTL 61: AVLLVILAVL ILVAIDMPRR TFGLTALAFI VGALGSMLAG YLGMYVTTRS ASRVAQAAAT 121: GGMGKALLVS WRAGAVMGLS LASIALLLIS GFYLVFRSVL PDDWAVPLVA LGFGASLVTL 181: FMRVGGGIYT KAADLGADLV GKVEAGIPED DPRNPGVIAD NVGDNVGDVA GMAADVYESY 241: IVTVTAAIFL AAILGLPTQF IEAIILFAAL ALVATFAGVN LLKTTGVKHP LSSISLAIYA 301: TIGLSVVLFF IGAFTLGLDS TKALALAATT SLGAVIAPLI VKITDYYTSY NYGPVRKIAE 361: QAKISPATVI ITGYGVGLMS AIPVIAVIVA VLGISYMIGY YTVPVSGFGE LSKYLAGIFG 421: TAMASVGLLV VAGIIITADS YGPVSDNAGG VVEMAGLPDE VREITDVLDS VGNTTKATTK 481: GYAIASAALA ALVLFIALIF EIVYSASKIL GKGIVDMISE SLSGLQLINA NVLIGAFLGV 541: ALVYFFSSRT LEAVGRTAME IVEEIRRQFR EKPGILEWKE QPDYARVVDI ATRRALGEFL 601: IPGLAAIVLP LITGLLLGWN ALAGLIMGAI VAGVPRALLM ANAGGAWDNA KKYIEIQGLK 661: KTEMHKAAVI GDTVGDPMKD TVGPSLNPLI KVLNTLSVVF TYVIVSTNIA LGIWPSGLLP 721: F