3.A.19.1.3
Get3 ATPase homologue of 349 aas and 0 TMSs that drives the insertion of tail anchored (TA) proteins into the endoplasmic reticulum membrane. The 3-d structure of the tetramer has been solved (Suloway et al. 2012). The tetramer generates a hydrophobic chamber that probably binds the single C-terminal TMS of the TA protein.
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| Accession Number: | Q58542 |
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| Protein Name: | Putative arsenical pump-driving ATPase |
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| Length: | 349 |
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| Molecular Weight: | 39919.00 |
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| Species: | Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) [243232] |
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| Substrate |
protein polypeptide chain |
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1: MLSKIKDSIN SLRGITEKKL EKKDGTKYIM FGGKGGVGKT TMSAATGVYL AEKGLKVVIV
61: STDPAHSLRD IFEQEFGHEP TKVKGYDNLY VVEIDPQKAM EEYKEKLKAQ IEENPFLGEM
121: LEDQLEMAAL SPGTDESAAF DVFLKYMDSN EFDVVIFDTA PTGHTLRFLG MPEVMDKYMT
181: KLIKLRKQMS GFMKMMKKLL PFGGKDEDID YDKMLEELEK MKERIVRARN ILSDPERTAF
241: RLVVIPEEMS ILESERAMKA LQKYGIPIDA VIVNQLIPED VQCDFCRARR ELQLKRLEMI
301: KEKFGDKVIA YVPLLRTEAK GIETLKQIAK ILYGEEEKEE QKIEQKVGQ