3.A.2.2.9 subunit c of the H+-pumping V-type ATPase. Found to be essential for bloodstream-form Trypanosoma brucei through a genome-wide RNAi screen (Schmidt et al. 2018).
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Accession Number: | Q38CL8 |
Protein Name: | V-type proton ATPase proteolipid subunit |
Length: | 191 |
Molecular Weight: | 19380.00 |
Species: | Trypanosoma brucei brucei (strain 927/4 GUTat10.1) [185431] |
Number of TMSs: | 5 |
Location1 / Topology2 / Orientation3: |
Vacuole membrane1 / Multi-pass membrane protein2 |
Substrate |
hydron |
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1: MKTQNLLFAA SAAVSAGAAA AGAVSCDEMY PQSAAFFGSM GCASALIFAN LGSAYGTAKS
61: GVGVAHLGIL HADRIMRGIV PVVMAGILGI YGLIVSVIIN NNIKTELHAY AAFSGYLHFG
121: AGLAAGLSSL AAGLSIGIAG DASVRAYGKQ EKIFVAMILM LIFAEALGLY GLIIALLMNN
181: TANKVNYGPC Q