3.A.3.1.14
Na+/K+-ATPase of 1227 aas and 10 TMSs. Involved in cell signaling, volume regulation, and
maintenance of electrochemical gradients (Morrill et al. 2016). Genomic analyses of the euryhaline model ciliate Paramecium duboscqui reveal adaptations to environmental salinity via changes in transporter gene expression (Fu et al. 2024).
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| Accession Number: | Q6BGF7 |
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| Protein Name: | Na+K+ ATPase alpha subunit, putative |
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| Length: | 1227 |
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| Molecular Weight: | 137542.00 |
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| Species: | Paramecium tetraurelia [5888] |
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| Number of TMSs: | 8 |
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| Substrate |
sodium(1+), potassium(1+) |
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1: MAQYRQLNEG DIPPINNPQI VTGFQILRQS VDLGLRQNQD ARKSSVKAAA LVSRQSQMYQ
61: QAKERGIVPN EVIVNYDAPT NTKQDLLKKA QNKGEEYRNM DEHKVDVIAL SQRYETSLTD
121: GLTQDQATAK NKQYGDNKLT EKKKKPWWIK LILEMVQPFS ILLWIASIMC FVLYGVNPEA
181: LGAKSNLWLA IILIAIILLT GSITYNQSAK ADALMEGFKN FLPQKCIAIR GGEKVEVPAE
241: KLVPGDIIEI KMGDKIPADV RIIQSREMKV DNSALTGECD PLLRVTELTS ENPLETKNLA
301: FFGTLCKEGS GKGLVIQIGD NTVMGQIADL ATGGETPETP LNIELKRFVI LISCIAVGLG
361: ILFLILSLVV EQASVDTAVG QAIGIIVANV PEGLLGCITV SLAITAKRLA DKQVLVKNLE
421: AVETLGSTSC ICSDKTGTLT QNKMTVANVW YDGLKRVALN KLKHGRNTEY EYDINDPTFR
481: DLHDCAIITS EAKFNIQAKD KATTNWLESP TIGDASETAL IKFFQPIEDI ENTRQRRQLV
541: ELSDKSLAKM PFNSTNKFSL CIVNWETQDS FYCVYIKGAP EKLWTFSSYL LVEGRNQPID
601: EQITQKFKSV NVSFGKGGER VLGFAKLHLP RSEFQKGYKF NLNSIDTLKF KLEGFTFLGL
661: LSLMDPPKET VPQAIKKCQS AGIKVIMVTG DQPPTAGAIA KQIGIITGKT VDDLLEENPS
721: MSYDEAFRLA PAIVIHGDMI VQALEEESQN GEYVPEHMKD RRLKSWCSKP QVVFARTSPA
781: QKLMIVRACQ YIGHVVGVTG DGVNDSPAIK QGDIGISMGI SGSDVTKDAA DMILLNDDFA
841: SIVDGVEEGR KIFDNLKKTI VYLLTSNITE VFPYVGEIAL GLPLPLSNAF ILTICIGTDI
901: LPAISFAYEE AEIDIMTRKP RKKDDHLVSL RLITHAYLLQ GIIATSAGFF SYFSTMNEYG
961: FPPQLLLNLM NTPYQKIPWP SIILANGSSY TPPPTTWVWD LPNMNNPFLT TQPYNPDWQQ
1021: APILTVEEGK SLDSSIGFQN IPLNWINPEI IYYDLRYIFV YYDQNYQRWF PTFEEWQNQN
1081: SDNLCRYFDR SDMLLEDNKY PINTNACFKT AALKYAQTSY FVAVVLVQWS NVFSCKQRKM
1141: SVIYSPINVV MFYGVLLETL IFICIVYIPG VNNWFGARPV DILNLGMPGL PYSMCLFCWE
1201: EMRKYFIRNY AKPSKYEPNF FEANSLW