3.A.3.2.44
Crayfish basolateral plasma membrane Ca2+-ATPase, PMCA, of 1190 aas (Wheatly et al. 2007). 80% identical to the human orthologue.
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| Accession Number: | Q6SLH6 |
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| Protein Name: | Calcium-transporting ATPase |
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| Length: | 1190 |
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| Molecular Weight: | 131139.00 |
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| Species: | Procambarus clarkii (Red swamp crayfish) [6728] |
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| Number of TMSs: | 8 |
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| Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
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| Substrate |
calcium(2+) |
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1: MGDDANSSIE FHPRPNQRRD GNQAGGFGCS LMELRSLMEL RGLEAVVKIQ EDYGDVEGLC
61: RRLKTSPTEG LADNTNDLEK RRQIYGQNFI PPKKPKTFLQ LVWEALQDVT LIILEIAAIV
121: SLGLSFYRPP GETGGGAAAG GAEDEGEAEA GWIEGAAILL SVVCVVLVTA FNDWSKEKQF
181: RGLQSRIEQE QKFTVVRNGQ VLQIPVAELV VGDIAQVKYG DLLPADGVLI QGNDLKIDER
241: SLTGESDHVR KSADKDPMLL SGTHVMEGSG RMVVTAVGVN SQTGIIFTLL GAGAEEEEVE
301: AKKRKKEAKK QRKKQKKGDS GEELIDANPK KQDGEMESNQ IKAKKQDGAA AMEMQPLKSA
361: EGGEADEEEE KKVNTPKKEK SVLQGKLTKL AVQIGKAGLV MSAITVIILV LYFGIETFVV
421: EGRPWTPVYI QYFVKFFIIG VTVLVVAVPE GLPLAVTISL AYSVKKMMKD NNLVRHLDAC
481: ETMGNATAIC SDKTGTLTTN RMTVVQSYIG DEHYKEIPDP GSLPPKILDL LVNAISINSA
541: YTTKILPPDK EGDLPRQVGN KTECALLGFV LDLKRDYQPI RDQIPEEKLY KVYTFNSVRK
601: SMSTVVPMRD GGFRIYSKGA SEIVLKKCSQ ILNRDGELRS FRPRDKDDMV RKVIEPMACD
661: GLRTICIAYR DFVRGCAEIN QVHFENEPNW DNENNIMSDL TCLAVVGIED PVRPEVPDAI
721: QKCQRAGITV RMVTGANINT ARAIASKCGI IQPGEDFLCL EGKEFNRRIR DESGCIEQER
781: IDKVWPKLRV LARSSPTDKH TLVKGIIDST TNDQRQVVAV TGDGTNDGPA LKKADVGFAM
841: GIAGTDVAKE ASDIILTDDN FTSIVKAVMW GRNVYDSISK FLQFQLTVNV VAVIVAFTGA
901: CITQDSPLKA VQMLWVNLIM DTFASLALAT EPPTESLLLR KPYGRTKPLI SRTMMKNILG
961: HAVYQLLIIF TLLFVGEGFF DIDSGRNAPL HSPPSEHYTI IFNTFVMMQL FNEINARKIH
1021: GERNVFDGIF SNPIFCTIVL GTFGIQIVIV QFGGKPFSCT PLPAEQWLWC LFVGAGELVW
1081: GQVMATIPTS QLKSLKGAGH EHRKDEMNAE DLNEGQEEID HAERELRRGQ ILWFRGLNRI
1141: QTQIEVVNAF KSGSSVQGAV RRPSSILSQN QDVTNVSTPS HASSGMPLAL