3.A.3.32.9 Heavy metal translocating P-type ATPase, P1B ATPase, with an N-terminal CoBaHMA domain indicative of a heavy metal associated (HMA) domain (Gaschignard et al. 2024). It has 737 aas and 8 TMSs in a 4 + 2 + 2 TMS arrangement and is from a delta proteobacterium NaphS2.
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Accession Number: | D8F5K4 |
Protein Name: | Heavy metal translocating P-type ATPase |
Length: | 737 |
Molecular Weight: | 80412.00 |
Species: | delta proteobacterium NaphS2 [88274] |
Number of TMSs: | 8 |
Location1 / Topology2 / Orientation3: |
Cell membrane1 |
Substrate |
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1: MAHHPEIDIR LCHAVPGRVR FRIPELRSSR VLADFLKNRL MKREDVEHAE TRLVTGSLII
61: RYDEDKITGP DFVEALQSQL PALVTRDLTK FSKDYVVPSE GKRKFRLFQS LGFYLLNAVA
121: LSGFMAFLFL RRLILGASIS QGPLSLTGLA AMFGAIPLFL RASQDLVQKE RMGLFPFLSV
181: SAVLAIFTGE ALAALEILWI LSIGTLLEAY ATERARKSVL ELLEVTPDRT FVLSEQKEIE
241: ISSREIRVGQ TVVVHAGMMI PVDGRVLKGE GLVDTSQITG RAKPEMCRKN NQVFAGTRVQ
301: QGSFHIRADR LGEETFLARI RHLVEISLSQ PTIAEKRADV LTARLTKLGL IATFFTFILT
361: RSFSRTFSVM LVMACPCATV LAASTAVAAA IANAARHRIL IKGGVHLEQL PNIDVICFDK
421: TGTLTAADLC VTTILTRAPG QPSDRVLQLA ASAEALATHP MATALITEAR RRNLELTQPT
481: QTDVSLGRGV SAVLGKDAVL VGNEGFLESN GIKTNYYHRK AVHFRSSGQS VVYVAKNGRL
541: QGIIAIHNSP RPGLSTVLDR LKEEGHPILY LVSGDSESVV QTMAAAYDFD NYRGDLLPHE
601: KSDLIKKMRG EGKRVMMVGD GVNDALVLSD ANIGVSMGAG GSDVAVEAAD IVLLRNDLNG
661: LLFLKDLSKK TLQIVDQNFW LATLTNAIGI IMAVPGWMPP AFSGVMHVGH SLGILINSGR
721: ILKWAPETKK ILTSAPS