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| Accession Number: | Q3MNJ6 |
| Protein Name: | Cation-transporting ATPase aka TcrA) |
| Length: | 811 |
| Molecular Weight: | 86816.00 |
| Species: | Enterococcus faecium (Streptococcus faecium) [1352] |
| Number of TMSs: | 9 |
| Location1 / Topology2 / Orientation3: | Cell membrane1 / Multi-pass membrane protein2 |
| Substrate | copper(1+) |
Cross database links:
| Pfam: | PF00122 PF00403 PF00702 |
|---|---|
Gene Ontology
GO:0016021
C:integral to membrane
GO:0005524
F:ATP binding
GO:0005507
F:copper ion binding
GO:0004008
F:copper-exporting ATPase activity
GO:0006754
P:ATP biosynthetic process
GO:0006825
P:copper ion transport
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References (2)[1] “tcrB, a gene conferring transferable copper resistance in Enterococcus faecium: occurrence, transferability, and linkage to macrolide and glycopeptide resistance.” Hasman H.et.al. 11959576 [2] “The tcrB gene is part of the tcrYAZB operon conferring copper resistance in Enterococcus faecium and Enterococcus faecalis.” Hasman H.et.al. 16151212
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External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MTCASCAQTV EKAAKKVRGV TQASVNLATE KLSIEYDEPT FSVENLQKAV DNSGYELIAQ 61: EGTTQTFAIE GMTCASCAQT IEKAVGKLSG VDKASVNLAT EKMQVSYNPS AISVSDVTGA 121: VSNSGYAAVL ETTETQDNSR AEKREKKEKR MKQLSNRFGI SIIFTIPLLI ISMGPMVGMP 181: LPNIVDPMIN AFNFSLLQLI LTLPIMVVSW EYFQKGFKTL FKGHPNMDSL IALGTAAAFV 241: YSLAATIGAG LGYGNFSDLL YYEVTGVILT LHTLGLFLEE RSKGQMSSAI EKLVNLVPKT 301: ARVIRNGVEQ EITVDEVALG DVIRVRPGES MPVDGVVVEG RTSVDESMLT GESIPVEKES 361: GDEVIGASIN KNGSIDYRAT RVGSDTTLSQ IIKLVEDAQG SKAPIARMAD IITRYFVPIV 421: IALAVLAGIA WLIAGQSGIF ILSVIITTLV IACPCALGLA TPTSIMVGTG KGAEHGVLIK 481: SGEALETTHN LDTIVFDKTG TLTEGKPIVT DILVTPLITK ENLLYYAASG ETGSEHPLGE 541: AIVQKSKEEN MTLAKPDHFE AIPGHGIRVE IEGKDMYIGN RKLMLEQKID LSSMEKESNR 601: LADEGKTPMY LSVDGELAGI IAVADTLKEN SMKAVKELRR RGVEVIMITG DNKRTAKAIA 661: KQVGIDSVLS EVLPEDKAEE VKKLQEAGKK VAMVGDGIND APALAQADIG IAVGSGTDVA 721: IESADIVLMR NDLTAVLTAI DLSHATLRNI KQNLFWAFAY NLVGIPVAMG LLYIFGGPLM 781: NPMFAAVAMS FSSVSVLLNA LRLRRFKPAV V