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| Accession Number: | Q8VPE6 |
| Protein Name: | Cation-transporting ATPase aka TcrB |
| Length: | 710 |
| Molecular Weight: | 76238.00 |
| Species: | Enterococcus faecium (Streptococcus faecium) [1352] |
| Number of TMSs: | 8 |
| Location1 / Topology2 / Orientation3: | Cell membrane1 / Multi-pass membrane protein2 |
| Substrate | copper(1+) |
Cross database links:
| Pfam: | PF00122 PF00702 |
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Gene Ontology
GO:0016021
C:integral to membrane
GO:0005524
F:ATP binding
GO:0004008
F:copper-exporting ATPase activity
GO:0006754
P:ATP biosynthetic process
GO:0006825
P:copper ion transport
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References (2)[1] “tcrB, a gene conferring transferable copper resistance in Enterococcus faecium: occurrence, transferability, and linkage to macrolide and glycopeptide resistance.” Hasman H.et.al. 11959576 [2] “The tcrB gene is part of the tcrYAZB operon conferring copper resistance in Enterococcus faecium and Enterococcus faecalis.” Hasman H.et.al. 16151212
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External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MRNNKKHSSH SHHNHGDMEH SKHDHNEMEH SQMDHSKMNH SAMDHSKMNH SQMDHSEMDH 61: GAMGGHAHHH HGSFKEIFLK SLPLGIAILL ITPMMDIQLP FQIIFPYADV VAAVLATILY 121: IYGGKPFYMG AKDEFNSKAP GMMSLITLGI TVSYAYSVYA VAARYVTGEH VMDFFFEFAT 181: LILIMLLGHW IEMKALGEAG DAQKALAELV PKDAHVVLED DSIETRPVSE LQVGDVIRVQ 241: AGENVPADGI IIRGESRVNE ALVTGESKPI EKNPGDEVIG GSTNGGGVLY VEIKQTGDKS 301: FISQVQALIS QAQGQSSRAE NLAQKVAGWL FYIAVIVALI ALVIWMIIAD VPTAVIFTVT 361: TLVIACPHAL GLAIPLVTAR STSLGASRGL LVKDRDALEL TTNADVMVLD KTGTLTTGEF 421: KVLDVELFND KYTKDEIVAL LSGIEGGSSH PIAQSIISYA EQQGIRPVSF DSIDVISGAG 481: VEGQANGHRY QLISQKAYRR NLDMDIPKGA TLSVLVENDE AIGAVALGDE LKPTSKDLIQ 541: ALKKNKIQPI MATGDNEKAA QGTAEILGID YLANQSPQDK YELVEKLKAE GKKVIMVGDG 601: VNDAPSLALA DVGIAVGAGT QVALDSADVI LTQSDPGDIE SFIELAQKTT RKMKENLVWG 661: AGYNFIAIPI AAGILAPIGI TLSPAVGAVL MSLSTVIVAI NAMTLKLDPK