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3.A.3.5.41
Cuprous ion (Cu+) exporter, CtpA (does not export Co2+, Mn2+, Ni2+, Zn2+ or Cu2+).  Km for Cu+ = 0.05 μM (León-Torres et al. 2015). 

Accession Number:P9WPU1
Protein Name:Copper-exporting P-type ATPase
Length:761
Molecular Weight:78851.00
Species:Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [83332]
Number of TMSs:8
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate

Cross database links:

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTTAVTGEHH ASVQRIQLRI SGMSCSACAH RVESTLNKLP GVRAAVNFGT RVATIDTSEA 
61:	VDAAALCQAV RRAGYQADLC TDDGRSASDP DADHARQLLI RLAIAAVLFV PVADLSVMFG 
121:	VVPATRFTGW QWVLSALALP VVTWAAWPFH RVAMRNARHH AASMETLISV GITAATIWSL 
181:	YTVFGNHSPI ERSGIWQALL GSDAIYFEVA AGVTVFVLVG RYFEARAKSQ AGSALRALAA 
241:	LSAKEVAVLL PDGSEMVIPA DELKEQQRFV VRPGQIVAAD GLAVDGSAAV DMSAMTGEAK 
301:	PTRVRPGGQV IGGTTVLDGR LIVEAAAVGA DTQFAGMVRL VEQAQAQKAD AQRLADRISS 
361:	VFVPAVLVIA ALTAAGWLIA GGQPDRAVSA ALAVLVIACP CALGLATPTA MMVASGRGAQ 
421:	LGIFLKGYKS LEATRAVDTV VFDKTGTLTT GRLQVSAVTA APGWEADQVL ALAATVEAAS 
481:	EHSVALAIAA ATTRRDAVTD FRAIPGRGVS GTVSGRAVRV GKPSWIGSSS CHPNMRAARR 
541:	HAESLGETAV FVEVDGEPCG VIAVADAVKD SARDAVAALA DRGLRTMLLT GDNPESAAAV 
601:	ATRVGIDEVI ADILPEGKVD VIEQLRDRGH VVAMVGDGIN DGPALARADL GMAIGRGTDV 
661:	AIGAADIILV RDHLDVVPLA LDLARATMRT VKLNMVWAFG YNIAAIPVAA AGLLNPLVAG 
721:	AAMAFSSFFV VSNSLRLRKF GRYPLGCGTV GGPQMTAPSS A