3.A.3.6.26
Cadmium/zinc resistance efflux pump, CadA of 910 aas and 8 TMSs (Maynaud et al. 2014).
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| Accession Number: | M5EWU5 |
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| Protein Name: | Heavy metal translocating P-type ATPase |
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| Length: | 910 |
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| Molecular Weight: | 94823.00 |
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| Species: | Mesorhizobium metallidurans STM 2683 [1297569] |
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| Number of TMSs: | 8 |
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| Location1 / Topology2 / Orientation3: |
Cell membrane1 |
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| Substrate |
cadmium(2+), zinc(2+) |
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1: MNEAVLKSRY RVAGMDCAAC AKKIDTAARR IDGVADVAVS VTAGTMTIDH SPKADMEKLA
61: KRVESLGYKV APLALAQVKA TAGAAPKSEG ASCTNPDHHH DHAGDDHSDH DHVDQDHSGH
121: DHSDHDHAGH DHASHGKTLE QRANAAGLIA ANANTILQSR YRVAGMDCAA CAKKIDTAAR
181: RVEGVQDVSV SVTAGTMTVD HSSKADMEKL AKRVESLGYK VAPIALGQAE AVGGAALRSD
241: PANSIDLDHD HLGHDHSDHD HSSHDKGKKA DVQDGAVAGL HGHDHGSEEG PWWKTSKARL
301: TILCGLALAA AFVLAKLVPE TAPWAFIVAM AVGLIPIARR AIMAALNGSP FTIETLMTIA
361: AVGAVIINAS EEAAAVVFLF LVGEMLEGVA AGRARASITA LASLVPKTAL LEVDGKTSEV
421: PAESLAVGST ILVRPGDRVP ADGTIISGES SIDESPMTGE SVPKRKLPED QVFAGTINQD
481: APIRVKVTAT AADNTIARII QLVEKAQESK APTERFIDRF STYYTPAVMI VAALVAIVPP
541: LVFGGLWNEW IYKGLAILLI GCPCALVIST PAAIAASLSA GARRGLLMKG GAVLETLGKI
601: TKVAFDKTGT LTEGKPKVTD IVAVGRTEAE TLALAADLEI GSSHPLAMAI LDEARKRDIN
661: PTSASEARAI GGEGIVGKVG GVELFFGSPK AAEKRCALTQ DLRDRIAKLN DEGKSVSVLL
721: AGRVVAGVIA MRDEPREDAK EGIEALKRLD VTAVMLTGDN KRTAAAIAKS LGLEPRAELL
781: PEDKQRIVGE LQKTGHIVGK VGDGINDAPA LAAANVGIAM GGGTDVALET ADAAVLHGRV
841: KDVANMIALS RATMSNIMQN ITISLGLKAV FLVTTVMGIT GLWPAILADT GATVIVTANA
901: MRLLGWRGLK