| |
|---|---|
| Accession Number: | P13587 |
| Protein Name: | ATN1 aka Pmr2ap aka ENa1 aka PMR2 aka HOR6 aka YDR040C aka YD6888.02C |
| Length: | 1091 |
| Molecular Weight: | 120357.00 |
| Species: | Saccharomyces cerevisiae (Baker's yeast) [4932] |
| Number of TMSs: | 10 |
| Location1 / Topology2 / Orientation3: | Cell membrane1 / Multi-pass membrane protein2 |
| Substrate | sodium(1+) |
Cross database links:
| DIP: | DIP-4493N |
|---|---|
| RefSeq: | NP_010325.1 |
| Entrez Gene ID: | 851610 |
| Pfam: | PF00689 PF00690 PF00122 PF00702 |
| KEGG: | sce:YDR040C |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0005886
C:plasma membrane
GO:0001950
C:plasma membrane enriched fraction
GO:0005524
F:ATP binding
GO:0008556
F:potassium-transporting ATPase activity
GO:0008554
F:sodium-exporting ATPase activity, phosphory...
GO:0006754
P:ATP biosynthetic process
GO:0042149
P:cellular response to glucose starvation
GO:0006972
P:hyperosmotic response
GO:0006813
P:potassium ion transport
GO:0009268
P:response to pH
GO:0009651
P:response to salt stress
GO:0006814
P:sodium ion transport
GO:0055085
P:transmembrane transport
| |
References (11)[1] “The yeast secretory pathway is perturbed by mutations in PMR1, a member of a Ca2+ ATPase family.” Rudolph H.K.et.al. 2526682 [2] “The PMR2 gene cluster encodes functionally distinct isoforms of a putative Na+ pump in the yeast plasma membrane.” Wieland J.et.al. 7664728 [3] “The nucleotide sequence of Saccharomyces cerevisiae chromosome IV.” Jacq C.et.al. 9169867 [4] “A PMR2 tandem repeat with a modified C-terminus is located downstream from the KRS1 gene encoding lysyl-tRNA synthetase in Saccharomyces cerevisiae.” Martinez R.et.al. 2046655 [5] “The yeast lysyl-tRNA synthetase gene. Evidence for general amino acid control of its expression and domain structure of the encoded protein.” Mirande M.et.al. 2903861 [6] “Multiple transduction pathways regulate the sodium-extrusion gene PMR2/ENA1 during salt stress in yeast.” Marquez J.A.et.al. 8612770 [7] “Overexpression of the sodium ATPase of Saccharomyces cerevisiae: conditions for phosphorylation from ATP and Pi.” Benito B.et.al. 9315618 | |
External Searches:
|
Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
|
|||
1: MGEGTTKENN NAEFNAYHTL TAEEAAEFIG TSLTEGLTQD EFVHRLKTVG ENTLGDDTKI 61: DYKAMVLHQV CNAMIMVLLI SMIISFAMHD WITGGVISFV IAVNVLIGLV QEYKATKTMN 121: SLKNLSSPNA HVIRNGKSET INSKDVVPGD ICLVKVGDTI PADLRLIETK NFDTDESLLT 181: GESLPVSKDA NLVFGKEEET SVGDRLNLAF SSSAVVKGRA KGIVIKTALN SEIGKIAKSL 241: QGDSGLISRD PSKSWLQNTW ISTKKVTGAF LGTNVGTPLH RKLSKLAVLL FWIAVLFAII 301: VMASQKFDVD KRVAIYAICV ALSMIPSSLV VVLTITMSVG AAVMVSRNVI VRKLDSLEAL 361: GAVNDICSDK TGTLTQGKML ARQIWIPRFG TITISNSDDP FNPNEGNVSL IPRFSPYEYS 421: HNEDGDVGIL QNFKDRLYEK DLPEDIDMDL FQKWLETATL ANIATVFKDD ATDCWKAHGD 481: PTEIAIQVFA TKMDLPHNAL TGEKSTNQSN ENDQSSLSQH NEKPGSAQFE HIAEFPFDST 541: VKRMSSVYYN NHNETYNIYG KGAFESIISC CSSWYGKDGV KITPLTDCDV ETIRKNVYSL 601: SNEGLRVLGF ASKSFTKDQV NDDQLKNITS NRATAESDLV FLGLIGIYDP PRNETAGAVK 661: KFHQAGINVH MLTGDFVGTA KAIAQEVGIL PTNLYHYSQE IVDSMVMTGS QFDGLSEEEV 721: DDLPVLPLVI ARCSPQTKVR MIEALHRRKK FCTMTGDGVN DSPSLKMANV GIAMGINGSD 781: VSKEASDIVL SDDNFASILN AVEEGRRMTD NIQKFVLQLL AENVAQALYL IIGLVFRDEN 841: GKSVFPLSPV EVLWIIVVTS CFPAMGLGLE KAAPDLMDRP PHDSEVGIFT WEVIIDTFAY 901: GIIMTGSCMA SFTGSLYGIN SGRLGHDCDG TYNSSCRDVY RSRSAAFATM TWCALILAWE 961: VVDMRRSFFR MHPDTDSPVK EFFRSIWGNQ FLFWSIIFGF VSAFPVVYIP VINDKVFLHK 1021: PIGAEWGLAI AFTIAFWIGA ELYKCGKRRY FKTQRAHNPE NDLESNNKRD PFEAYSTSTT 1081: IHTEVNIGIK Q