3.A.3.9.7
P-type Ca2+ ATPase of 1041 aas and 12 TMSs. Found to be essential for bloodstream-form Trypanosoma brucei through a genome-wide RNAi screen (Schmidt et al. 2018).
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| Accession Number: | Q38CW7 |
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| Protein Name: | Calcium motive P-type ATPase, putative |
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| Length: | 1041 |
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| Molecular Weight: | 113976.00 |
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| Species: | Trypanosoma brucei brucei (strain 927/4 GUTat10.1) [185431] |
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| Number of TMSs: | 10 |
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| Substrate |
calcium ion |
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1: MTGSGGREPI DVATGTAPAV DKGETIPTKY EPHNKWWSCD IPTTLSLVQL EDPSVGVPSS
61: DVSRRAAELG HNHIPLKGGP SALWILAQQF LNSITLILTI VMVISAVFED WAEFGVVLFL
121: ILFNALLGFY QEYSAEKSLE SLKAMTAGSA KVLRDGTVQV IFIDEVVVGD VIIIEQGSSV
181: PADCRIIESS GLEVDEALLT GEALPVVKHT NEIPDPGNSC ALGDRKNMVY RNTTVTQGRA
241: RAVVCAAGVD TEMGKLAARL ADGTGSGRTE LMRKLDLMMY ILFAVCLGLA LVVFAANRFK
301: FKRSTLSYAT AVAVAILPES LVAVVTVSMT FSVRNMARQR CIVRKLAVME VLGNVTDICS
361: DKTGTLTENK MVVKKALIGI DNELVVTGAP HERYGTFIRE EGEEHVNMLE VYETNKLAVE
421: FMRCAALCST TVLHPDSEDA DLLKGSGNPT EVAIQVMTWK ADAPRNKLEN QGWECIAEYP
481: FDSKIKRMST AWYNSETKSL YLCTKGAPER VIDLCTTKML ESGKLAPITD DDRQELTKKI
541: TSLASHGLRT ICFSMNASTV NEFPIPDDDT FQVTHPRETI EQSLTFLGIV GIYDPPRPES
601: RPSVIACQHA GIVVRMLTGD HAITARSIAT ILNIITAKDG EDPLKVLTGP EFDRIDMATI
661: EEWPDLPLVV GRCSPESKVK MIECLHKRGR TVAMTGDGFN DSPSIKFADV GCAMGSGTDV
721: TKGVADLIIT DDNFATIVKA VAEGRRISQN IRKFVLHLLS GNVSEVIALI CGLPIRYMGE
781: ALFVLSPVEI LWLNLCTSAP PATGLSLDPA SADVLLVPPH TAGLFTFELV TDFLVYGFWL
841: GGLALSAFVW IIYGINDGPK GENCNERTAV GCEMVWQARG TAFGILYFGL LVHSYTVRHP
901: RQSVIFMKWF DNPWIYGSVI VCSLLFFPIV YVPAIARNIF QHHSLTWHWG MMVPAVIIFV
961: GLCELHKIFK NCLFPVKRPV IDRSDEEEYR RFAVPGPDDD RDVESIAEDQ LRQSFVSAAG
1021: SIASGGRRRK GRRFGGKGGK M