| TCID | Name | Domain | Kingdom/Phylum | Protein(s) |
|---|---|---|---|---|
|
3.D.7.1.1 | H2:heterodisulfide oxidoreductase, HHO. Two protons are consumed in the cytoplasm while two protons are released in the periplasm, contributing to the pmf (Simon et al., 2008; Welte and Deppenmeier 2013). The HdrD/E-type heterodisulfide reductase probably can function independently of the other subunits. | Archaea |
Euryarchaeota | HHO of Methanosarcina mazei Göl VhoA: (CAA58114) VhoG: (CAA58113) VhoC: (CAA58115) HdrD: (gbY09870) HdrE: (gbY09870) |
|
3.D.7.1.2 | Putative heterodisulfide oxidoreductase, HdrDE (Pires et al. 2003). HdrD, 423 aas and 1 TMS; HdrE, 394 aas and 6 TMSs. | Bacteria |
Thermodesulfobacteriota | HdrDE of Desulfovibrio desulfuricans |
|
3.D.7.1.3 | Putative heterodisulfide reductase, HdrDE (Pires et al. 2003). HdrD, 663 aas and 6 TMSs; HdrE, 392 aas and 6 TMSs. | Bacteria |
Chlorobiota | HdrDE of Chlorobium phaeobacteroides |
|
3.D.7.1.4 | Cytoplasmic adenylylsulfate reductase, ApsAB, with its associated electron transfer protein complex, QmoABC which may take electrons from a periplasmic electron donor or from the membrane quinone pool (Zane et al. 2010; Bertran et al. 2018). | Bacteria |
Thermodesulfobacteriota | ApsAB/QmoABC of Desulfovibrio vulgaris |
|
3.D.7.1.5 | CoB--CoM heterodisulfide reductase with 4 different proteins subunits plus two probable auxillary proteins: OLS30722 - OLS30727. | Archaea |
Candidatus Thorarchaeota | CoB--CoM heterodisulfide reductase of Candidatus Thorarchaeota archaeon AB_25 |
|
3.D.7.1.6 | Putative cytoplasmic adenylylsulfate reductase, ApsAB, with its associated electron transfer protein complex, QmoABC which may take electrons from a periplasmic electron donor or from the membrane quinone pool and transfer them to ApsAB (Zane et al. 2010; Bertran et al. 2018). | Bacteria |
Thermodesulfobacteriota | ApsAB/QmoABC of Desulfococcus multivorans |
|
3.D.7.2.1 | Membrane-bound H2 oxidizing hydrogenase, HydAB (Guiral et al., 2005). HydC has not been identified, but adjacent to hydB is an open reading frame (ORF; AAC07057; 226aas) showing similarity to cytochromes that could be HydC. | Bacteria |
Aquificota | HydAB of Aquifex aeolicus HydA (large subunit; 564 aas) (AAC07046) HydB (small subunit; 349 aas) (AAC07047) |
|
3.D.7.2.2 | Membrane-bound Ni/Fe-hydrogenase complex, HydABC (Simon et al., 2008). HydC (P31875) resembles 5.A.3.5.1 (e-6), 5.A.3.2.1 (e-5), and 3.D.7.1.1 (e-4). Two protons are consumed in the cytoplasm while two protons are released in the periplasm, contributing to the pmf (Simon et al., 2008). | Bacteria |
Campylobacterota | HydABC of Wolinella succinogenes HydA (P31884) HydB (P31883) HydC (P31875) |
|
3.D.7.2.3 | Hydrogenase HyaABCDEF, important for H2 oxidation during fermentation (Zbell and Maier 2009). | Bacteria |
Pseudomonadota | HyaABCDEF of Salmonella enterica suspecies enterica serovar Typhimurium HyaA (367 aas, 4 TMSs) HyaB (600 aas, 0 TMSs) HyaC (347 aas, 4 TMSs) HyaD (198 aas, 0 TMSs) HyaE (134 aas, 0 TMSs) HyaF (353 aas, 0 TMSs) |
|
3.D.7.2.4 | F420-non reducing hydrogenase subunits A, D and G of 472, 141, and 308 aas, respectively, with 0, 0 and 3-5 TMSs, respectively. It is a [NiFe] hydrogenase and part of a complex that provides reducing equivalents for heterodisulfide reductase (Stojanowic et al. 2003). Also called HdrABC. This system is also found in Archeoglobus profundus DSM5631 (acc#s P84625, P84624, P84627) and Candidatus Prometheoarchaeum syntrophicum strain MK-D1 (Imachi et al. 2020). | Archaea |
Euryarchaeota | MvhADG of Methanothermobacter marburgensis |
|
3.D.7.2.5 | Hydrogenase-2, HybABCDEFG including the subunits of the hydrogenase as well as three maturation proteins (HybD, HybF and HybG). | Bacteria |
Pseudomonadota | HybABCDEFG of E. coli |