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Accession Number: | P69786 |
Protein Name: | PTS system glucose-specific EIICB component PTGB aka PTSG aka GLCA aka UMG aka B1101 |
Length: | 477 |
Molecular Weight: | 50677.00 |
Species: | Escherichia coli [83333] |
Number of TMSs: | 10 |
Location1 / Topology2 / Orientation3: | Cell inner membrane1 / Multi-pass membrane protein2 |
Substrate | D-glucopyranose |
Cross database links:
DIP: | DIP-29833N |
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RefSeq: | AP_001727.1 NP_415619.1 |
Entrez Gene ID: | 945651 |
Pfam: | PF00367 PF02378 |
BioCyc: | EcoCyc:PTSG-MONOMER ECOL168927:B1101-MONOMER |
KEGG: | ecj:JW1087 eco:b1101 |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0005886
C:plasma membrane
GO:0005355
F:glucose transmembrane transporter activity
GO:0016301
F:kinase activity
GO:0005515
F:protein binding
GO:0008982
F:protein-N(PI)-phosphohistidine-sugar phosph...
GO:0005351
F:sugar:hydrogen symporter activity
GO:0015758
P:glucose transport
GO:0009401
P:phosphoenolpyruvate-dependent sugar phospho...
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References (11)[1] “Glucose permease of the bacterial phosphotransferase system. Gene cloning, overproduction, and amino acid sequence of enzyme IIGlc.” Erni B.et.al. 3023349 [2] “A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map.” Oshima T.et.al. 8905232 [3] “The complete genome sequence of Escherichia coli K-12.” Blattner F.R.et.al. 9278503 [4] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.” Hayashi K.et.al. 16738553 [5] “Cysteine phosphorylation of the glucose transporter of Escherichia coli.” Meins M.et.al. 8505292 [6] “Involvement of a novel transcriptional activator and small RNA in post-transcriptional regulation of the glucose phosphoenolpyruvate phosphotransferase system.” Vanderpool C.K.et.al. 15522088 [7] “Global topology analysis of the Escherichia coli inner membrane proteome.” Daley D.O.et.al. 15919996 [8] “Translational repression is sufficient for gene silencing by bacterial small noncoding RNAs in the absence of mRNA destruction.” Morita T.et.al. 16549791 [9] “The glucose transporter of Escherichia coli. Assignment of the 1H, 13C and 15N resonances and identification of the secondary structure of the soluble IIB domain.” Golic Grdadolnik S.et.al. 8112346 [10] “Solution structure of the IIB domain of the glucose transporter of Escherichia coli.” Eberstadt M.et.al. 8784182 [11] “Glucose transporter of Escherichia coli: NMR characterization of the phosphocysteine form of the IIB(Glc) domain and its binding interface with the IIA(Glc) subunit.” Gemmecker G.et.al. 9200688
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Structure: | |
External Searches:
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Analyze:
Predict TMSs (Predict number of transmembrane segments) | ||||
FASTA formatted sequence |
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1: MFKNAFANLQ KVGKSLMLPV SVLPIAGILL GVGSANFSWL PAVVSHVMAE AGGSVFANMP 61: LIFAIGVALG FTNNDGVSAL AAVVAYGIMV KTMAVVAPLV LHLPAEEIAS KHLADTGVLG 121: GIISGAIAAY MFNRFYRIKL PEYLGFFAGK RFVPIISGLA AIFTGVVLSF IWPPIGSAIQ 181: TFSQWAAYQN PVVAFGIYGF IERCLVPFGL HHIWNVPFQM QIGEYTNAAG QVFHGDIPRY 241: MAGDPTAGKL SGGFLFKMYG LPAAAIAIWH SAKPENRAKV GGIMISAALT SFLTGITEPI 301: EFSFMFVAPI LYIIHAILAG LAFPICILLG MRDGTSFSHG LIDFIVLSGN SSKLWLFPIV 361: GIGYAIVYYT IFRVLIKALD LKTPGREDAT EDAKATGTSE MAPALVAAFG GKENITNLDA 421: CITRLRVSVA DVSKVDQAGL KKLGAAGVVV AGSGVQAIFG TKSDNLKTEM DEYIRNH