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| Accession Number: | P20166 |
| Protein Name: | PTS system, glucose-specific IICBA component aka EIICBA-Glc aka Glucose-permease IICBA component aka Phosphotransferase enzyme II, CBA component aka EC 2.7.1.69 aka EII-Glc/EIII-Glc |
| Length: | 699 |
| Molecular Weight: | 75525.00 |
| Species: | Bacillus subtilis [1423] |
| Number of TMSs: | 13 |
| Location1 / Topology2 / Orientation3: | Cell membrane1 / Multi-pass membrane protein2 |
| Substrate | glucose |
Cross database links:
| RefSeq: | NP_389272.1 |
|---|---|
| Entrez Gene ID: | 939255 |
| Pfam: | PF00358 PF00367 PF02378 |
| KEGG: | bsu:BSU13890 |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0005886
C:plasma membrane
GO:0005355
F:glucose transmembrane transporter activity
GO:0016301
F:kinase activity
GO:0008982
F:protein-N(PI)-phosphohistidine-sugar phosph...
GO:0005351
F:sugar:hydrogen symporter activity
GO:0015758
P:glucose transport
GO:0009401
P:phosphoenolpyruvate-dependent sugar phospho...
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References (8)[1] “Cloning and nucleotide sequence of the ptsG gene of Bacillus subtilis.” Zagorec M.et.al. 1508157 [2] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.” Kunst F.et.al. 9384377 [3] “Phosphoenolpyruvate:sugar phosphotransferase system of Bacillus subtilis: nucleotide sequence of ptsX, ptsH and the 5'-end of ptsI and evidence for a ptsHI operon.” Gonzy-Treboul G.et.al. 2497294 [4] “The glucose permease of the phosphotransferase system of Bacillus subtilis: evidence for IIGlc and IIIGlc domains.” Gonzy-Treboul G.et.al. 1956301 [5] “The glucose permease of Bacillus subtilis is a single polypeptide chain that functions to energize the sucrose permease.” Sutrina S.L.et.al. 2120236 [6] “Structure of the IIA domain of the glucose permease of Bacillus subtilis at 2.2-A resolution.” Liao D.-I.et.al. 1911744 [7] “Polypeptide backbone resonance assignments and secondary structure of Bacillus subtilis enzyme IIIglc determined by two-dimensional and three-dimensional heteronuclear NMR spectroscopy.” Fairbrother W.J.et.al. 1906345 [8] “High-resolution solution structure of Bacillus subtilis IIAglc.” Chen Y.et.al. 9593197
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| Structure: | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MFKALFGVLQ KIGRALMLPV AILPAAGILL AIGNAMQNKD MIQVLHFLSN DNVQLVAGVM 61: ESAGQIVFDN LPLLFAVGVA IGLANGDGVA GIAAIIGYLV MNVSMSAVLL ANGTIPSDSV 121: ERAKFFTENH PAYVNMLGIP TLATGVFGGI IVGVLAALLF NRFYTIELPQ YLGFFAGKRF 181: VPIVTSISAL ILGLIMLVIW PPIQHGLNAF STGLVEANPT LAAFIFGVIE RSLIPFGLHH 241: IFYSPFWYEF FSYKSAAGEI IRGDQRIFMA QIKDGVQLTA GTFMTGKYPF MMFGLPAAAL 301: AIYHEAKPQN KKLVAGIMGS AALTSFLTGI TEPLEFSFLF VAPVLFAIHC LFAGLSFMVM 361: QLLNVKIGMT FSGGLIDYFL FGILPNRTAW WLVIPVGLGL AVIYYFGFRF AIRKFNLKTP 421: GREDAAEETA APGKTGEAGD LPYEILQAMG DQENIKHLDA CITRLRVTVN DQKKVDKDRL 481: KQLGASGVLE VGNNIQAIFG PRSDGLKTQM QDIIAGRKPR PEPKTSAQEE VGQQVEEVIA 541: EPLQNEIGEE VFVSPITGEI HPITDVPDQV FSGKMMGDGF AILPSEGIVV SPVRGKILNV 601: FPTKHAIGLQ SDGGREILIH FGIDTVSLKG EGFTSFVSEG DRVEPGQKLL EVDLDAVKPN 661: VPSLMTPIVF TNLAEGETVS IKASGSVNRE QEDIVKIEK