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Accession Number: | P77272 |
Protein Name: | N-Acetylmuramic acid porter, MurP (YfeV) |
Length: | 474 |
Molecular Weight: | 49802.00 |
Species: | Escherichia coli [83333] |
Number of TMSs: | 10 |
Location1 / Topology2 / Orientation3: | Cell inner membrane1 / Multi-pass membrane protein2 |
Substrate | N-acetyl-alpha-D-muramic acid |
Cross database links:
RefSeq: | AP_003023.1 NP_416924.1 |
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Entrez Gene ID: | 946894 |
Pfam: | PF00367 PF02378 |
BioCyc: | EcoCyc:MONOMER0-5 ECOL168927:B2429-MONOMER |
KEGG: | ecj:JW2422 eco:b2429 |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0005886
C:plasma membrane
GO:0016301
F:kinase activity
GO:0008982
F:protein-N(PI)-phosphohistidine-sugar phosph...
GO:0005351
F:sugar:hydrogen symporter activity
GO:0009401
P:phosphoenolpyruvate-dependent sugar phospho...
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References (7)[1] “Construction of a contiguous 874-kb sequence of the Escherichia coli-K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features.” Yamamoto Y.et.al. 9205837 [2] “The complete genome sequence of Escherichia coli K-12.” Blattner F.R.et.al. 9278503 [3] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.” Hayashi K.et.al. 16738553 [4] “Identification of a phosphotransferase system of Escherichia coli required for growth on N-acetylmuramic acid.” Dahl U.et.al. 15060041 [5] “Global topology analysis of the Escherichia coli inner membrane proteome.” Daley D.O.et.al. 15919996 [6] “MurQ etherase is required by Escherichia coli in order to metabolize anhydro-N-acetylmuramic acid obtained either from the environment or from its own cell wall.” Uehara T.et.al. 16452451 [7] “The transcriptional factors MurR and catabolite activator protein regulate N-acetylmuramic acid catabolism in Escherichia coli.” Jaeger T.et.al. 18723630
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External Searches:
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Analyze:
Predict TMSs (Predict number of transmembrane segments) | ||||
FASTA formatted sequence |
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1: MAKEISSELL NTILTRVGGP GNIASCGNCM TRLRLGVHDS SLVDPNIKTL EGVKGVILTS 61: DQVQVVFGPG KAHRAAKAMS ELLGEAPVQD AAEIAAQNKR QLKAKQTSGV QQFLAKFATI 121: FTPLIPGFIA AGLLLGIATL IATVMHVPAD AQGTLPDALN FMKVFSKGLF TFLVILVGYN 181: AAQAFGGTGV NGAIIAALFL LGYNPAATTG YYAGFHDFFG LPIDPRGNII GVLIAAWACA 241: RIEGMVRRFM PDDLDMLLTS LITLLITATL AYLIIMPLGG WLFEGMSWLF MHLNSNPFGC 301: AVLAGLFLIA VVFGVHQGFI PVYLALMDSQ GFNSLFPILS MAGAGQVGAA LALYWRAQPH 361: SALRSQVRGA IIPGLLGVGE PLIYGVTLPR MKPFVTACLG GAAGGLFIGL IAWWGLPMGL 421: NSAFGPSGLV ALPLMTSAQG ILPAMAVYAG GILVAWVCGF IFTTLFGCRN VNLD