Search TCDB: (?)
TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


4.A.2.1.9
The FrzABC PTS putative transporter (promotes bacterial fitness under stress conditions and promotes fimbrial (fim) gene expression indirectly (Rouquet et al., 2009). Might transport D-tagatose, D-psicose and/or D-sorbose, or a disaccharide of these (Rouquet et al. 2009); involved in environmental sensing, host adaptation and virulence (Patron et al. 2015).

Accession Number:Q1R4S9
Protein Name:Putative phosphotransferase system (PTS), fructose-specific
Length:156
Molecular Weight:17425.00
Species:Escherichia coli (strain UTI89 / UPEC) [364106]
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate sorbose, psicose derivative, D-tagatose

Cross database links:

RefSeq: YP_543166.1   
Entrez Gene ID: 3991484   
Pfam: PF00359   
BioCyc: ECOL364106:UTI89_C4207-MONOMER   
KEGG: eci:UTI89_C4207   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0008982 F:protein-N(PI)-phosphohistidine-sugar phosph...
GO:0005351 F:sugar:hydrogen symporter activity
GO:0009401 P:phosphoenolpyruvate-dependent sugar phospho...

References (1)

[1] “Identification of genes subject to positive selection in uropathogenic strains of Escherichia coli: a comparative genomics approach.”  Chen S.L.et.al.   16585510

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence 
1:	MDITKILNTN RVILDMQATN KAEAIEELTN LLKKDGAIDC RETFIKDVWQ REAEGSTGFE 
61:	NHIAIPHGKS SAVINTTLAI GRTRQDIPWE TLDGSSVRCI ILFAVRLEDQ NTTHIRLLSQ 
121:	VAGALADDDI IEQLLVETSP QKIIDLFSQY AQSDVF