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4.A.4.1.1
Glucitol porter (also transports 2-C-methyl-D-erythritol, an isoprenoid biosynthetic precursor; Testa et al., 2004)

Accession Number:P56580
Protein Name:PTHB aka SRLE aka GUTE aka B2703
Length:319
Molecular Weight:33332.00
Species:Escherichia coli [83333]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate glucitol

Cross database links:

RefSeq: AP_003270.1    YP_026181.1   
Entrez Gene ID: 948933   
Pfam: PF07663    PF03612   
BioCyc: EcoCyc:GUTA-MONOMER   
KEGG: ecj:JW5430    eco:b2703   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0016301 F:kinase activity
GO:0008982 F:protein-N(PI)-phosphohistidine-sugar phosph...
GO:0009401 P:phosphoenolpyruvate-dependent sugar phospho...

References (6)

[1] “Glucitol-specific enzymes of the phosphotransferase system in Escherichia coli. Nucleotide sequence of the gut operon.”  Yamada M.et.al.   3553176
[2] “Construction of a contiguous 874-kb sequence of the Escherichia coli-K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features.”  Yamamoto Y.et.al.   9205837
[3] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[4] “Escherichia coli K-12: a cooperatively developed annotation snapshot -- 2005.”  Riley M.et.al.   16397293
[5] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[6] “Global topology analysis of the Escherichia coli inner membrane proteome.”  Daley D.O.et.al.   15919996

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence
1:	MTHIRIEKGT GGWGGPLELK ATPGKKIVYI TAGTRPAIVD KLAQLTGWQA IDGFKEGEPA 
61:	EAEIGVAVID CGGTLRCGIY PKRRIPTINI HSTGKSGPLA QYIVEDIYVS GVKEENITVV 
121:	GDATPQPSSV GRDYDTSKKI TEQSDGLLAK VGMGMGSTVA VLFQSGRDTI DTVLKTILPF 
181:	MAFVSALIGI IMASGLGDWI AHGLAPLASH PLGLVMLALI CSFPLLSPFL GPGAVIAQVI 
241:	GVLIGVQIGL GNIPPHLALP ALFAINAQAA CDFIPVGLSL AEARQDTVRV GVPSVLVSRF 
301:	LTGAPTVLIA WFVSGFIYQ