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4.A.6.1.11
Mannose enzyme II complex, IIAB, IIC, IID. IIC/IID serve allows entry of some bacteriocins including pediocin (class IIa), lactococcin A and lactococcin Z (class IIc) (Kjos et al., 2011; Daba et al. 2018). Transports and phosphorylates Glucose, Mannose and Glucosamine.  The IID component is the probably receptor for several bacteriocins, subclass IIa bacteriocins (pediocin-like; pediocins) and subclass IId ones - lactococcin A (LcnA), lactococcin B (LcnB), garvicin Q (GarQ), and garvicins A, B and C (GarA-C) (Tymoszewska et al. 2018). Individual amino acids localized mostly in the sugar channel-forming transmembrane parts of subunit IIC or in the extracellular parts of IID likely are involved in the interaction with each bacteriocin, and these have been specified (Tymoszewska et al. 2018).

Accession Number:D2BKY8
Protein Name:Mannose-specific PTS system, IIC component
Length:270
Molecular Weight:27563.00
Species:Lactococcus lactis subsp. lactis (strain KF147) [684738]
Number of TMSs:7
Substrate mannose

Cross database links:

Entrez Gene ID: 8679300   
Pfam: PF03609   
KEGG: llk:LLKF_1869   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0008982 F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GO:0009401 P:phosphoenolpyruvate-dependent sugar phosphotransferase system

References (2)

[1] “Genome-scale genotype-phenotype matching of two Lactococcus lactis isolates from plants identifies mechanisms of adaptation to the plant niche.”  Siezen R.J.et.al.   18039825
[2] “Complete genome sequence of Lactococcus lactis subsp. lactis KF147, a plant-associated lactic acid bacterium.”  Siezen R.J.et.al.   20348266

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MEYGVLSVIL VIVVAFLAGL EGILDQWQFH QPIIACSLIG IVTGHASAGI ILGGSLQLIA 
61:	LGWANVGAAV APDAALASIA SSILMVQSNN FDLTHIMGTI VPAAILLATA GLVLTTLVRM 
121:	LSVVLVHQAD RAAENGSYSG VEMWHFIALI CQGLRIAIPA GLLLVISPDA IQKALAAIPP 
181:	VISGGLAVGG GMVVAVGYAM VINLMATREV WPFFFLGFAL APISELTLIA TGVLGVVIAI 
241:	VYLNLQASGG SGNGTASSSG DPIGDILNDY