TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


4.A.6.1.16
Constitutively synthesized (at a low level) sensor, MpoABCD, controlling expression of the man operon-encoding the ManLMN (MptACD) transport system (see TC# 4.A.6.1.15). The Mpo system interacts with and phosphorylates ManR, the transcriptional regulator of the man operon (Aké et al. 2011). This system is a mannose PTS system, IIABCDMan or MpoABCD that transports its sugar substrates slowly and serves as a glucose (sugar substrate) sensor to regulate the activity of ManR by a phosphorylation/dephosphorylation mechanism. MptACD (TC# 4.A.6.1.15) is the primary inducible sugar transport system. ManR is an activator that is inactivated by a phosphorylation/dephosphorylation mechanism (Aké et al. 2011; Zébré et al. 2015).

Accession Number:Q8Y8W0
Protein Name:Lmo0782 protein
Length:270
Molecular Weight:28202.00
Species:Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) [169963]
Number of TMSs:8
Substrate mannose

Cross database links:

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence
1:	MSAIQLILVF LVSCISGMGS ILDEWQTHRP LIACTLIGLV LGDITTGIII GGTLEMIALG 
61:	WMNIGAAVAP DAALASIIST ILVITGGQDI SVGISLAIPL AALGQVLTIL VRTITVAFQH 
121:	MADKAGKEGN LRSLDWIHVT ALLLQAMRIA IPAVIVAVTV GTSAVENLLN AIPDVIVNGL 
181:	NVAGGFIVVV GYAMVINMMS AKYLMPFFFL GFVVAAFTQF NLVALGVLGL VAAIIYIQLN 
241:	PKYQLKEAIQ QYGGGGGGRS ADDLDDDLDD