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|---|---|
| Accession Number: | Q9XIA9 |
| Protein Name: | Long chain acyl-CoA synthetase 2 |
| Length: | 665 |
| Molecular Weight: | 74389.00 |
| Species: | Arabidopsis thaliana (Mouse-ear cress) [3702] |
| Location1 / Topology2 / Orientation3: | Endoplasmic reticulum1 |
| Substrate | fatty acid |
Cross database links:
| Entrez Gene ID: | 841367 |
|---|---|
| Pfam: | PF00501 |
| KEGG: | ath:AT1G49430 |
Gene Ontology
GO:0005783
C:endoplasmic reticulum
GO:0009506
C:plasmodesma
GO:0005524
F:ATP binding
GO:0031957
F:very long-chain fatty acid-CoA ligase activity
GO:0010143
P:cutin biosynthetic process
GO:0050832
P:defense response to fungus
GO:0010311
P:lateral root formation
GO:0010025
P:wax biosynthetic process
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References (12)[1] “Arabidopsis contains nine long-chain acyl-coenzyme A synthetase genes that participate in fatty acid and glycerolipid metabolism.” Shockey J.M.et.al. 12177484 [2] “Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.” Theologis A.et.al. 11130712 [3] “Empirical analysis of transcriptional activity in the Arabidopsis genome.” Yamada K.et.al. 14593172 [4] “Arabidopsis contains a large superfamily of acyl-activating enzymes. Phylogenetic and biochemical analysis reveals a new class of acyl-coenzyme a synthetases.” Shockey J.M.et.al. 12805634 [5] “The acyl-CoA synthetase encoded by LACS2 is essential for normal cuticle development in Arabidopsis.” Schnurr J.et.al. 14973169 [6] “Osmotic regulation of root system architecture.” Deak K.I.et.al. 15960613 [7] “A permeable cuticle in Arabidopsis leads to a strong resistance to Botrytis cinerea.” Bessire M.et.al. 17396154 [8] “The transcription factor WIN1/SHN1 regulates Cutin biosynthesis in Arabidopsis thaliana.” Kannangara R.et.al. 17449808 [9] “Mutations in LACS2, a long-chain acyl-coenzyme A synthetase, enhance susceptibility to avirulent Pseudomonas syringae but confer resistance to Botrytis cinerea in Arabidopsis.” Tang D.et.al. 17434992 [10] “Root system architecture in Arabidopsis grown in culture is regulated by sucrose uptake in the aerial tissues.” Macgregor D.R.et.al. 18952782 | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MSLAADNVLL VEEGRPATAE HPSAGPVYRC KYAKDGLLDL PTDIDSPWQF FSEAVKKYPN 61: EQMLGQRVTT DSKVGPYTWI TYKEAHDAAI RIGSAIRSRG VDPGHCCGIY GANCPEWIIA 121: MEACMSQGIT YVPLYDSLGV NAVEFIINHA EVSLVFVQEK TVSSILSCQK GCSSNLKTIV 181: SFGEVSSTQK EEAKNQCVSL FSWNEFSLMG NLDEANLPRK RKTDICTIMY TSGTTGEPKG 241: VILNNAAISV QVLSIDKMLE VTDRSCDTSD VFFSYLPLAH CYDQVMEIYF LSRGSSVGYW 301: RGDIRYLMDD VQALKPTVFC GVPRVYDKLY AGIMQKISAS GLIRKKLFDF AYNYKLGNMR 361: KGFSQEEASP RLDRLMFDKI KEALGGRAHM LLSGAAPLPR HVEEFLRIIP ASNLSQGYGL 421: TESCGGSFTT LAGVFSMVGT VGVPMPTVEA RLVSVPEMGY DAFSADVPRG EICLRGNSMF 481: SGYHKRQDLT DQVLIDGWFH TGDIGEWQED GSMKIIDRKK NIFKLSQGEY VAVENLENTY 541: SRCPLIAQIW VYGNSFESFL VGVVVPDRKA IEDWAKLNYQ SPNDFESLCQ NLKAQKYFLD 601: ELNSTAKQYQ LKGFEMLKAI HLEPNPFDIE RDLITPTFKL KRPQLLQHYK GIVDQLYSEA 661: KRSMA