| |
|---|---|
| Accession Number: | Q9UKG9 |
| Protein Name: | CrOT or COT |
| Length: | 612 |
| Molecular Weight: | 70178.00 |
| Species: | Homo sapiens (Human) [9606] |
| Location1 / Topology2 / Orientation3: | Peroxisome1 |
| Substrate | Carnitine O-octanoyl |
Cross database links:
| RefSeq: | NP_066974.2 |
|---|---|
| Entrez Gene ID: | 54677 |
| Pfam: | PF00755 |
| OMIM: |
606090 gene |
Gene Ontology
GO:0005782
C:peroxisomal matrix
GO:0008458
F:carnitine O-octanoyltransferase activity
GO:0006631
P:fatty acid metabolic process
GO:0006091
P:generation of precursor metabolites and energy
GO:0006810
P:transport
| |
References (4)[1] “Molecular cloning and expression of human carnitine octanoyltransferase: evidence for its role in the peroxisomal beta-oxidation of branched-chain fatty acids.” Ferdinandusse S.et.al. 10486279 [2] “Human chromosome 7: DNA sequence and biology.” Scherer S.W.et.al. 12690205 [3] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [4] “Structural model of a malonyl-CoA-binding site of carnitine octanoyltransferase and carnitine palmitoyltransferase I: mutational analysis of a malonyl-CoA affinity domain.” Morillas M.et.al. 11790793
| |
External Searches:
|
|
Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
|
|||
1: MENQLAKSTE ERTFQYQDSL PSLPVPSLEE SLKKYLESVK PFANQEEYKK TEEIVQKFQS 61: GIGEKLHQKL LERAKGKRNW LEEWWLNVAY LDVRIPSQLN VNFAGPAAHF EHYWPPKEGT 121: QLERGSITLW HNLNYWQLLR KEKVPVHKVG NTPLDMNQFR MLFSTCKVPG ITRDSIMNYF 181: RTESEGRSPN HIVVLCRGRA FVFDVIHEGC LVTPPELLRQ LTYIHKKCHS EPDGPGIAAL 241: TSEERTRWAK AREYLIGLDP ENLALLEKIQ SSLLVYSMED SSPHVTPEDY SEIIAAILIG 301: DPTVRWGDKS YNLISFSNGV FGCNCDHAPF DAMIMVNISY YVDEKIFQNE GRWKGSEKVR 361: DIPLPEELIF IVDEKVLNDI NQAKAQYLRE ASDLQIAAYA FTSFGKKLTK NKMLHPDTFI 421: QLALQLAYYR LHGHPGCCYE TAMTRHFYHG RTETMRSCTV EAVRWCQSMQ DPSVNLRERQ 481: QKMLQAFAKH NKMMKDCSAG KGFDRHLLGL LLIAKEEGLP VPELFTDPLF SKSGGGGNFV 541: LSTSLVGYLR VQGVVVPMVH NGYGFFYHIR DDRFVVACSA WKSCPETDAE KLVQLTFCAF 601: HDMIQLMNST HL