TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


4.D.1.1.2
IcaA of 412 aas and 4 (1 + 3) TMSs.

Accession Number:Q54066
Protein Name:Poly-beta-1,6-N-acetyl-D-glucosamine synthase
Length:412
Molecular Weight:47750.00
Species:Staphylococcus epidermidis (strain ATCC 35984 / RP62A) [176279]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate glycosyl group

Cross database links:

Entrez Gene ID: 3240428   
Pfam: PF00535   
KEGG: ser:SERP2293   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0008375 F:acetylglucosaminyltransferase activity
GO:0042710 P:biofilm formation

References (3)

[1] “Molecular basis of intercellular adhesion in the biofilm-forming Staphylococcus epidermidis.”  Heilmann C.et.al.   8809760
[2] “Insights on evolution of virulence and resistance from the complete genome analysis of an early methicillin-resistant Staphylococcus aureus strain and a biofilm-producing methicillin-resistant Staphylococcus epidermidis strain.”  Gill S.R.et.al.   15774886
[3] “Characterization of the N-acetylglucosaminyltransferase activity involved in the biosynthesis of the Staphylococcus epidermidis polysaccharide intercellular adhesin.”  Gerke C.et.al.   9660830

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence
1:	MHVFNFLLFY PIFMSIYWIV GSIYYFFIKE KPFNRSLLVK SEHQQVEGIS FLLACYNESE 
61:	TVQDTLSSVL SLEYPEKEII IINDGSSDNT AEIIYDFKKN HDFKFVDLEV NRGKANALNE 
121:	GIKQASYEYV MCLDADTVID DDAPFYMIED FKKNPKLGAV TGNPRIRNKS SILGKIQTIE 
181:	YASIIGCIKR SQSLAGAINT ISGVFTLFKK SALKDVGYWD TDMITEDIAV SWKLHLFDYE 
241:	IKYEPRALCW MLVPETIGGL WKQRVRWAQG GHEVLLRDFW PTIKTKKLSL YILMFEQIAS 
301:	ITWVYIVLCY LSFLVITANI LDYTYLKYSF SIFFFSSFTM TFINIIQFTV ALFIDSRYEK 
361:	KNIVGLIFLS WYPTLYWVIN AAVVIMAFPK ALKRKKGGYA TWSSPDRGNI QR