8.A.104.1.8
Serine/Threonine protein kinase of 741 aas, 4 N-terminal TMSs, and possibly 2 or 3 central TMSs The kinase domain is like those of 9.A.15.1.1 and 9.B.45.1.3.
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| Accession Number: | D8HIS0 |
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| Protein Name: | Serine/threonine protein kinase |
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| Length: | 741 |
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| Molecular Weight: | 79848.00 |
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| Species: | Amycolatopsis mediterranei (strain U-32) [749927] |
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| Number of TMSs: | 4 |
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| Substrate |
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| Entrez Gene ID: |
9442435
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| Pfam: |
PF00069
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| KEGG: |
amd:AMED_8299
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GO:0004674
F:protein serine/threonine kinase activity
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[1] “Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.” Zhao W. et.al. 20567260
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1: MTRPATTLPP RSGSNSTTVV QAVTVLMGTV VGLTFLFGFG NVLNLALRLD VPTWVAPLVA
61: PAVDLSVLGL LLGIRQLALA VATPRQLRPA RRLLFFASAV TLALNVADPI VAGEYGKAAF
121: DAVGPLLLIG WAEVGPGLLR ALTITRQPGD AMFDDAKPVQ AAFADEPTAV RQAALGSSGE
181: DTKPNSAPTD GRSSRTESTM VNDEAAPPVE RPLLAGRYRV DGSLGRGGMS EVFHGYDERL
241: DRRVAIKLLR PPSPGSVPVA PNSPEAVEIL DTLNRDRKRF LREIRTTAQL EHPGTPAVYD
301: TGVETAPDGS TQLWLVMQLL RGSTLEATLD HTDYTTSPPS LAWAAAIATQ IAAVLADVHR
361: VDIVHRDIKP ANVMIVDGGL VKVLDFGIAI LRGAGALPRL TQVDRTVGTP AYMSPEQWLG
421: QAVTSASDIY SLGCLFYELL VGDVPFHATT DMPLRARHQL SAVPSVRARR TDIPVAVDTL
481: VTSMLAKDAQ RRPSAEAVYD ALMPLASAPS DTSVEGENRD PTSPFRRPLL APARRERLAG
541: GRDKLTDTEF EQLTANVQVL LDNDRPAEAI NLLEDGVERA RHDPALTLRL RHYLAAALFY
601: AGEYTRAASL FDVVGRDYRE HLPFADPYVL DCAYHAGHAY AEIGKPDKAL PQLRFYVLNA
661: KTSADEDAVA KVLESRFVIA QMLGAAGHPD EALTELEAVR PLLAEAFGAD STQVRNVDKQ
721: IARLRSGWEH GSPQGRGQSD R