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8.A.114.1.7 Golgi electrogenic, voltage-dependent, Mg²⁺-transporting palmitoyltransferase, Huntington-interacting protein, HIP14 (ZDHHC13) (Up-regulated with low [Mg²⁺]; Km =0.8 mM; regulated by autopalmitoylation) (Goytain et al., 2008).
Accession Number:	Q8IUH4
Protein Name:	Probable palmitoyltransferase ZDHHC13
Length:	622
Molecular Weight:	70861.00
Species:	Homo sapiens (Human) [9606]
Number of TMSs:	6
Location¹ / Topology² / Orientation³:	Membrane¹ / Multi-pass membrane protein²
Substrate

RefSeq:	NP_001001483.1 NP_061901.2
Entrez Gene ID:	54503
Pfam:	PF00023 PF01529
OMIM:	612815 gene
KEGG:	hsa:54503
Gene Ontology GO:0016021 C:integral to membrane GO:0008415 F:acyltransferase activity GO:0004871 F:signal transducer activity GO:0008270 F:zinc ion binding GO:0043123 P:positive regulation of I-kappaB kinase/NF-k...
References (5) [1] “HIP14, a novel ankyrin domain-containing protein, links huntingtin to intracellular trafficking and endocytosis.” Singaraja R.R.et.al. 12393793 [2] “Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.” Matsuda A.et.al. 12761501 [3] “Complete sequencing and characterization of 21,243 full-length human cDNAs.” Ota T.et.al. 14702039 [4] “Human chromosome 11 DNA sequence and analysis including novel gene identification.” Taylor T.D.et.al. 16554811 [5] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MEGPGLGSQC RNHSHGPHPP GFGRYGICAH ENKELANARE ALPLIEDSSN CDIVKATQYG 
61:	IFERCKELVE AGYDVRQPDK ENVSLLHWAA INNRLDLVKF YISKGAVVDQ LGGDLNSTPL 
121:	HWAIRQGHLP MVILLLQHGA DPTLIDGEGF SSIHLAVLFQ HMPIIAYLIS KGQSVNMTDV 
181:	NGQTPLMLSA HKVIGPEPTG FLLKFNPSLN VVDKIHQNTP LHWAVAAGNV NAVDKLLEAG 
241:	SSLDIQNVKG ETPLDMALQN KNQLIIHMLK TEAKMRANQK FRLWRWLQKC ELFLLLMLSV 
301:	ITMWAIGYIL DFNSDSWLLK GCLLVTLFFL TSLFPRFLVG YKNLVYLPTA FLLSSVFWIF 
361:	MTWFILFFPD LAGAPFYFSF IFSIVAFLYF FYKTWATDPG FTKASEEEKK VNIITLAETG 
421:	SLDFRTFCTS CLIRKPLRSL HCHVCNCCVA RYDQHCLWTG RCIGFGNHHY YIFFLFFLSM 
481:	VCGWIIYGSF IYLSSHCATT FKEDGLWTYL NQIVACSPWV LYILMLATFH FSWSTFLLLN 
541:	QLFQIAFLGL TSHERISLQK QSKHMKQTLS LRKTPYNLGF MQNLADFFQC GCFGLVKPCV 
601:	VDWTSQYTMV FHPAREKVLR SV

8.A.114.1.7
Golgi electrogenic, voltage-dependent, Mg²⁺-transporting palmitoyltransferase, Huntington-interacting protein, HIP14 (ZDHHC13) (Up-regulated with low [Mg²⁺]; Km =0.8 mM; regulated by autopalmitoylation) (Goytain et al., 2008).

Cross database links:

Gene Ontology

References (5)

External Searches:

Analyze:

8.A.114.1.7Golgi electrogenic, voltage-dependent, Mg2+-transporting palmitoyltransferase, Huntington-interacting protein, HIP14 (ZDHHC13) (Up-regulated with low [Mg2+]; Km =0.8 mM; regulated by autopalmitoylation) (Goytain et al., 2008).

Cross database links:

Gene Ontology

References (5)

External Searches:

Analyze:

8.A.114.1.7
Golgi electrogenic, voltage-dependent, Mg²⁺-transporting palmitoyltransferase, Huntington-interacting protein, HIP14 (ZDHHC13) (Up-regulated with low [Mg²⁺]; Km =0.8 mM; regulated by autopalmitoylation) (Goytain et al., 2008).