8.A.126.1.2
GTPase-activating protein (GAP), skywalker (Sky) of 587 aas, for Rab35 which
regulates synaptic vesicle (SV) protein recycling and turnover at neuromuscular junctions (Uytterhoeven et al. 2011). The N-terminal domain of this protein show sequence similarity with family 8.A.87, but the C-terminal domain shows greater seqence similarity with 8.A.116.1.1.
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| Accession Number: | Q9VIH7 |
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| Protein Name: | GTPase-activating protein skywalker |
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| Length: | 587 |
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| Molecular Weight: | 67328.00 |
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| Species: | Drosophila melanogaster (Fruit fly) [7227] |
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| Location1 / Topology2 / Orientation3: |
Cytoplasmic vesicle1 / Peripheral membrane protein2 |
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| Substrate |
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1: MPYHRGGDAS SQADKLSGIV EESDLYEGFA PHVETSEIKT LDFYNLPKQT GKEPALRSYT
61: EIQQLLQQGK KRDVKNILRE NSWPINSPIR AQLWPMLCGQ HQTKQQMLDG FYWEMVHQVF
121: GTTELSEKPI MLPAFVDATH CLPYHLTSTG RAVADRIVNV LGYDCPDITY SPVLYPITSI
181: LLHFMSEEEA YICLAGLVGS KEKVFINQTK LQHEVTWKTV MQIAKKHTKS ATSYFQRICP
241: GLKLERIFMD WCWWILAGLP FQHLVRIMDC YFHEGIKVLY RVALVILNLF HKECQSNNEW
301: SPDNIKNDIG NALIKFCKKI PVSPAKLLHA AFSIRGLSTQ YISRIFIKTE MLLKSRSVLT
361: SGSKQLIKSR SSDNLPTSQS QVNIQMMSHT LTIREHFGLP GTKNFIKTWT DRQFLFTLWS
421: WLPVRITMYQ PVLLYTTEEH GCSLTTFYVR VEQHEPTLLM IKTCNNEVFG AYCSSRWFER
481: NVKDDKGQRQ AYFGTGETFL FSLYPERAKY PWVGIEGDKD LGHSSELFMA ADSKMITIGG
541: GEGQAIWMDE NIRFGKTDSC KTFNNPPLCP SGDFEIRVLE VYGFVGI