8.A.128.1.1
Signal adaptor protein and TYRO protein tyrosine kinase-binding protein, KARAP/DAP12/TYROBP, of 113 aas and 2 N-terminal TMSs.  It is an adapter protein which non-covalently associates with activating receptors found on the surface of a variety of immune cells to mediate signaling and cell activation following ligand binding by the receptors (Dietrich et al. 2000).  See family description and UniProt (O43914) for more information. Human NKG2F can associate with DAP12 (Kim et al. 2004).