8.A.132.1.1
The Supressor of Lurcher 1, SOL1, or interferon alpha/beta receptor 1, IFNAR1, of 557 aas and 2 TMSs, one N-terminal and one C-terminal. SOL1 proteins regulate ionotropic glutamate receptor desensitization (Walker et al. 2006). SOL1 is an accessory protein requlred for glutamate-gated currents by Glr-1 (Zheng et al. 2004). This protein has an internal duplication and belongs to the FN3 superfamily. Its trafficking and signaling have been reported (Zanin et al. 2020).
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| Accession Number: | P17181 |
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| Protein Name: | Interferon alpha/beta receptor 1 |
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| Length: | 557 |
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| Molecular Weight: | 63525.00 |
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| Species: | Homo sapiens (Human) [9606] |
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| Number of TMSs: | 1 |
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| Location1 / Topology2 / Orientation3: |
Cell membrane1 / Single-pass type I membrane protein2 |
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| Substrate |
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1: MMVVLLGATT LVLVAVAPWV LSAAAGGKNL KSPQKVEVDI IDDNFILRWN RSDESVGNVT
61: FSFDYQKTGM DNWIKLSGCQ NITSTKCNFS SLKLNVYEEI KLRIRAEKEN TSSWYEVDSF
121: TPFRKAQIGP PEVHLEAEDK AIVIHISPGT KDSVMWALDG LSFTYSLVIW KNSSGVEERI
181: ENIYSRHKIY KLSPETTYCL KVKAALLTSW KIGVYSPVHC IKTTVENELP PPENIEVSVQ
241: NQNYVLKWDY TYANMTFQVQ WLHAFLKRNP GNHLYKWKQI PDCENVKTTQ CVFPQNVFQK
301: GIYLLRVQAS DGNNTSFWSE EIKFDTEIQA FLLPPVFNIR SLSDSFHIYI GAPKQSGNTP
361: VIQDYPLIYE IIFWENTSNA ERKIIEKKTD VTVPNLKPLT VYCVKARAHT MDEKLNKSSV
421: FSDAVCEKTK PGNTSKIWLI VGICIALFAL PFVIYAAKVF LRCINYVFFP SLKPSSSIDE
481: YFSEQPLKNL LLSTSEEQIE KCFIIENIST IATVEETNQT DEDHKKYSSQ TSQDSGNYSN
541: EDESESKTSE ELQQDFV