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8.A.228.1.1 CRMP2 (DPYSL2) of 572 aas. It regulates the activity of Na²⁺ channel, Na_v1.7 preferentially (Gomez et al. 2023), thereby eliminating chronic neuropathic pain. See family description for details.
Accession Number:	Q16555
Protein Name:	Dihydropyrimidinase-related protein 2
Length:	572
Molecular Weight:	62294.00
Species:	Homo sapiens (Human) [9606]
Location¹ / Topology² / Orientation³:	Cytoplasm¹
Substrate

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MSYQGKKNIP RITSDRLLIK GGKIVNDDQS FYADIYMEDG LIKQIGENLI VPGGVKTIEA 
61:	HSRMVIPGGI DVHTRFQMPD QGMTSADDFF QGTKAALAGG TTMIIDHVVP EPGTSLLAAF 
121:	DQWREWADSK SCCDYSLHVD ISEWHKGIQE EMEALVKDHG VNSFLVYMAF KDRFQLTDCQ 
181:	IYEVLSVIRD IGAIAQVHAE NGDIIAEEQQ RILDLGITGP EGHVLSRPEE VEAEAVNRAI 
241:	TIANQTNCPL YITKVMSKSS AEVIAQARKK GTVVYGEPIT ASLGTDGSHY WSKNWAKAAA 
301:	FVTSPPLSPD PTTPDFLNSL LSCGDLQVTG SAHCTFNTAQ KAVGKDNFTL IPEGTNGTEE 
361:	RMSVIWDKAV VTGKMDENQF VAVTSTNAAK VFNLYPRKGR IAVGSDADLV IWDPDSVKTI 
421:	SAKTHNSSLE YNIFEGMECR GSPLVVISQG KIVLEDGTLH VTEGSGRYIP RKPFPDFVYK 
481:	RIKARSRLAE LRGVPRGLYD GPVCEVSVTP KTVTPASSAK TSPAKQQAPP VRNLHQSGFS 
541:	LSGAQIDDNI PRRTTQRIVA PPGGRANITS LG

8.A.228.1.1
CRMP2 (DPYSL2) of 572 aas. It regulates the activity of Na²⁺ channel, Na_v1.7 preferentially (Gomez et al. 2023), thereby eliminating chronic neuropathic pain. See family description for details.

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8.A.228.1.1CRMP2 (DPYSL2) of 572 aas. It regulates the activity of Na2+ channel, Nav1.7 preferentially (Gomez et al. 2023), thereby eliminating chronic neuropathic pain. See family description for details.

Cross database links:

External Searches:

Analyze:

8.A.228.1.1
CRMP2 (DPYSL2) of 572 aas. It regulates the activity of Na²⁺ channel, Na_v1.7 preferentially (Gomez et al. 2023), thereby eliminating chronic neuropathic pain. See family description for details.