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|---|---|
| Accession Number: | P42838 |
| Protein Name: | LEM3 |
| Length: | 414 |
| Molecular Weight: | 47438.00 |
| Species: | Saccharomyces cerevisiae (Baker's yeast) [4932] |
| Number of TMSs: | 2 |
| Location1 / Topology2 / Orientation3: | Cell membrane1 / Multi-pass membrane protein2 |
| Substrate | |
Cross database links:
| DIP: | DIP-4598N |
|---|---|
| RefSeq: | NP_014076.1 |
| Entrez Gene ID: | 855393 |
| Pfam: | PF03381 |
| KEGG: | sce:YNL323W |
Gene Ontology
GO:0005783
C:endoplasmic reticulum
GO:0016021
C:integral to membrane
GO:0005886
C:plasma membrane
GO:0005515
F:protein binding
GO:0007166
P:cell surface receptor linked signaling pathway
GO:0045332
P:phospholipid translocation
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References (8)[1] “Sequencing analysis of a 15.4 kb fragment of yeast chromosome XIV identifies the RPD3, PAS8 and KRE1 loci, five new open reading frames.” Maftahi M.et.al. 7645347 [2] “The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications.” Philippsen P.et.al. 9169873 [3] “A novel membrane protein, Ros3p, is required for phospholipid translocation across the plasma membrane in Saccharomyces cerevisiae.” Kato U.et.al. 12133835 [4] “Lem3p is essential for the uptake and potency of alkylphosphocholine drugs, edelfosine and miltefosine.” Hanson P.K.et.al. 12842877 | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MVNFDLGQVG EVFRRKDKGA IVSGDNPEEE EDVDASEFEE DEVKPVRTKN RRPKEDAFTQ 61: QRLAAINPVL TPRTVLPLYL LIAVVFVIVG GCILAQNSKV DEVTIYYQDC MTNATSSWSD 121: IPSEHWQFVF HKYKTYNTAP QWRFVDDESD DFTKQRGTCQ IRFTTPSDMK NNVYLNYVLE 181: KFAANHRRYV LSFSEDQIRG EDASYETVHD ATGINCKPLS KNADGKIYYP CGLIANSMFN 241: DTFPLQLTNV GDTSNNYSLT NKGINWESDK KRYKKTKYNY TQIAPPPYWE KMYPDGYNET 301: NIPDIQDWEE FQNWMRPGAF DKITKLIRIN KNDTLPAGEY QLDIGLHWPV LEFNGKKGIY 361: LTHGSHLGGR NPFLGIVYLI GGCICAAMAL ILLTFWLFGG RKIADASSLS WNMK